Results 301 to 310 of about 31,235,632 (381)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

In the Light of Healthcare Professionals: Beliefs About Chronic Low Back Pain. [PDF]

Medicina (Kaunas)
Péter B, Georgescu A, Popovici IM, Popescu L, Szabó-Csifó T, Radu LE, Fagaras PS.   +6 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

An Effective Team: Active Learning Also Needs the Sage on a Stage. [PDF]

J Med Educ Curric Dev
Bordonaro M.
europepmc   +1 more source

Child mortality and community-level education : an analysis of the impact of other women's education on child mortality in sub-Saharan Africa

, 2006
Camilla Kristiansen
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Specific micronutrient practices drive dietary quality in Ethiopia's industrial urban communities. [PDF]

J Health Popul Nutr
Tamire E, Abebe Z.
europepmc   +1 more source

Space Human Activity and Education of Spiritual Persons of Space Other Planetary Future in the Third Millennium

, 2014
N. V. Polischuk
openalex   +1 more source

Impact of Primary Spoken Language as a Social Determinant of Health on Cardiopulmonary Education and Use: Pilot Study. [PDF]

West J Emerg Med
LeNeave C, Meier B, Liffert H, Perkins JC.   +3 more
europepmc   +1 more source