Results 191 to 200 of about 605,734 (239)

Stroke awareness and response among university students in five Middle Eastern and North African countries: a multicenter cross-sectional study. [PDF]

Front Public Health
Alnajjar AZ, Abouelmagd ME, Marwan M, Alsalloum T, Mady A, Bushara N, Nabil Y, Krayim A, Masoud M, Abdelmeseh M, Daoud A, Alaa M, Faisal R, Saad M.   +13 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Knowledge, attitudes, and practices regarding osteoporosis among hormone receptor-positive breast cancer patients: a cross-sectional study. [PDF]

Front Public Health
Chen X, Xu R, Sun X, Huang X, Chen L, Liu J, Li X, Pan L, Cheng Y.   +8 more
europepmc   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Hair care product use among pregnant women of color: protocol for a feasibility educational intervention. [PDF]

Front Reprod Health
Tsui F, Vilfranc CL, Llanos AAM, Houghton LC, Franklin J, More V, Manz KE, Pennell KD, Terry MB, Shepard P, Barrett E, Walker DAH, McDonald JA.   +12 more
europepmc   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Innovative educational technology for visually impaired learners using a 3D-Printed foot reflexology robot. [PDF]

MethodsX
Nabudda K, Nabudda K, Kitprathaung N, Phumpho S, Poungthong P, Kongrungchok A.   +5 more
europepmc   +1 more source

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Psychosocial risk for substance use in 80,000 Mexican undergraduates: mental health and academic strain. [PDF]

Front Public Health
Martinez-Gonzalez MF, Alvarez-Lozada LA, Verdines-Pérez AM, Quiroga-Garza A, Jacobo-Baca G, Elizondo-Omaña R, Guzman-Lopez S, Del Río-Muñoz SE, Muñoz-Maldonado GE, Tamez-Gonzalez G, Castillo-Elizondo JA, Salinas-Zertuche A.   +11 more
europepmc   +1 more source