Results 51 to 60 of about 298,488 (263)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Editorial: Entrepreneurship Education

Horyzonty Wychowania, 2014
Education plays a key role in shaping the attitudes, skills and culture, hence the actions of the European Union in recent years have aimed at promoting entrepreneurship as a separate course taught at all levels of education, from elementary up to the ...
Krzysztof Wach
doaj  

A metric profile of research highlighting teacher training in Science Education in Brazil

Investigações em Ensino de Ciências, 2019
This paper focuses on what current literature indicates about the need to learn about the teacher training research field in a wide-ranging and profound manner. Within this framework, the objective was to outline a metric profile of the research field of
Julio César Castilho Razera, Carla Maria Santana Matos, Fernando Bastos   +2 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Merit Pay and Social Work

Social Work and Society, 2011
An economization of many social fields in Germany and other countries is under way, such as in the arts, journalism, education and science. Economic considerations have the upper hand in academic education (e.g., the introduction of tuition fees), while ...
Ursula H. Werling
doaj   +2 more sources

STEM: Scientific Database for Technical Vocational Education and Training at the Secondary Level

RAC: Revista de Administração Contemporânea
Objective: the fields of science, technology, engineering, and mathematics (STEM) influence economic, social, and scientific development. Research on these subjects is mostly found in primary, secondary, and higher education, as compared to vocational ...
Jéssica Trigo da Fonseca, Suylan de Almeida Midlej e Silva   +1 more
doaj   +1 more source

Open Educational Resources in Higher Education

Issues and Trends in Educational Technology, 2018
Open Educational Resources (OERs) are changing the learning and teaching landscape in many different fields. In the area of higher education, OERs are swiftly becoming important elements in support of Open Educational Practices (OEPs) and the Open ...
Margherita Berti
doaj   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Educação ainda que tardia: a exclusão da escola e a reinserção de adultos das camadas populares em um programa de EJA

Revista Brasileira de Educação, 2003
This research sought to comprehend the impacts which the experience of premature exclusion from school and that of second chance schooling have on the life of working class adults, privileging the narrative of former students of a programme of ...
Geovânia Lúcia dos Santos
doaj  

Legal Education And Challenges Of Contemporary Developments In Nigeria

International Journal of Clinical Legal Education, 2014
The development of any society is anchored on the existence of enabling environment for imparting legal education. Technological breakthrough and globalization among other things has made the provision of sound legal education to would-be lawyers and ...
Bagoni Bukar
doaj   +1 more source