Results 51 to 60 of about 1,886,316 (243)
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Why to get a 2nd diploma? Is it life-long learning or the outcome of state intervention in educational choices? [PDF]
This paper analyzes the determinants and labour market effects of further higher education studies of graduates, the factors that induce them to switch to other fields (switching decision) and in comparison the determinants of deciding upon “deepening ...
Júlia Varga
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Non-Traditional Entrants to the Profession of Teaching: Motivations and Experiences of Second-Career Educators [PDF]
, 2011 Individuals entering the teaching profession from other fields have much to offer in terms of practical experience in fields such as business, private industry, law enforcement, and the military.
Lamport, Ph.D., Mark A. +1 more
core +1 more source
Insiders, Outsiders, and Straddlers: A New Writing Fellows Program in Theory, Context, and Practice [PDF]
, 2014 There seems little question that writing centers have been increasingly visible and accessible (Jablonski; Nagelhout and Rutz; Spigelman and Grobman).
Macauley, William J. Jr
core +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Academic Recognition of Military Experience in STEM Education [PDF]
, 2013 Recent calls for increases in science, technology, engineering, and math (STEM) education attainment and veterans' education success have created a platform for examining how veterans with military experience in STEM fields can more efficiently complete ...
Meg Mitcham
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Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
QUALITY OF THE ACADEMIC PROGRAMMES [PDF]
The main issue addressed by this paper refers to the quality of training and education on project management – is it different than the perception of quality of training and education in other fields, if so, where, in what aspects, who should be ...
Constanta Nicoleta BODEA +2 more
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