Results 81 to 90 of about 1,886,316 (243)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

5 Months of Haskell : Programming languages as just other programs. Contribution toward a field of computer science education.

open access: yes, 2019
The following is understood as a contribution toward a field of com-puter science education : a reflection of 5 months of learning the functionalprogramming language Haskell; out of which has emerged for us that pro-gramming languages are ‘just other programs’.
openaire   +2 more sources

Barriers to Pursuing STEM-Related Careers: Perceptions of Hispanic Girls Enrolled in Advanced High School STEM Courses [PDF]

open access: yes, 2018
Researchers indicate that the United States has fallen behind other nations in science, technology, engineering, and mathematics (STEM) education (President\u27s Council of Advisors on Science and Technology, 2010, 2012).
Bustamante, Rebecca M.   +2 more
core   +1 more source

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

open access: yesFEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel   +13 more
wiley   +1 more source

How Europe can deliver: Optimising the division of competences among the EU and its member states [PDF]

open access: yes, 2017
This study aims to give guidance for a better-performing EU through an improved allocation of competences between the European Union and its member states.
Berger, Melissa   +5 more
core  

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

Navigating the Field of English Higher Education in Kazakhstan: Advocating for Habitus and Capital Engagement of Speakers of Languages other than English

open access: yes
In this paper, we focus on speakers of languages other than English to explore the impact of English medium of instruction (EMI) on the internationalisation of higher education in Kazakhstan. As postcolonial scholars of colour, we acknowledge that our historical and colonial legacies shape our positionality, epistemologies and worldviews, leading to ...
null michelle.bedeker, Munyaradzi Hwami
openaire   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

ICCTE 2010 Conference Review

open access: yes, 2010
This past May, the Ninth Biennial Conference of the ICCTE took place at LeTourneau University in Longview Texas. About 75 faculty members from a number of colleges and universities gathered to share their research, to fellowship together and to enjoy the
Headley, Scot
core  

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