Results 91 to 100 of about 376,761 (310)

Footnotes, Endnotes, and HTML5: Blogging and the future of literary criticism [PDF]

open access: yes, 2016
Conference paper presented at the ACCUTE (Association of Canadian College and University Teachers of English), Calgary 2016. Literary scholars were among the earliest adopters of digital dissemination of research; indeed, the field of Digital ...

core  

Linking early geospatial documents, one place at a time: annotation of geographic documents with Recogito [PDF]

open access: yes, 2015
Recogito is an open source tool for the semi-automatic annotation of place references in maps and texts. It was developed as part of the Pelagios 3 research project, which aims to build up a comprehensive directory of places referred to in early maps and
Barker, Elton   +3 more
core   +3 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

RISK AVERSION AND MAJOR CHOICE: EVIDENCE FROM ITALIAN STUDENTS [PDF]

open access: yes
Does the choice of the field of study depend on individual risk aversion? The direction of the relationship between individual risk attitudes and type of college major chosen is potentially ambiguous.
Francesca Gioia, Maria De Paola
core  

As humanidades e as ciências: disjunções e confluências [PDF]

open access: yes, 2014
The present volume offers a selection of the essays presented at the XV Colóquio de Outono organized by the research unit Centro de Estudos Humanísticos (Universidade do Minho) in November 2013, under the global topic Humanities and Sciences ...

core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Investigating the Citations Received by Journals of Directory of Open Access Journals from ISI Web of Science’s Articles

open access: yesInternational Journal of Information Science and Management, 2012
In this research, the citations received by DOAJ’s journals from the ISI Web of Science’s articles in 2003 to 2008 were studied and compared. The citations received by the journals in five fields (Arts & Humanities, Social Sciences, Pure Sciences ...
R. Saadat, A. Shabani
doaj  

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