Results 61 to 70 of about 376,761 (310)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Theoretical and Behavioral Conformity in Scientific Ethics Norms of Students [PDF]

Taḥqīqāt-i Farhangī-i Īrān, 2016
This article aims to achieve the theoretical and behavioral preferences on scientific Ethics norms among PhD students and the level of conformity and unconformity of theoretical and behavioral preferences on scientific Ethics norms among PhD students. It
Shahla Khalafi, Mohammad Reza Javadi Yeganeh, Mehrdad Navabakhsh   +2 more
doaj   +1 more source

Digital Humanities Best Practices: Engaging a Collaborator [PDF]

, 2015
The “Engaging a Collaborator” best practices document is intended as a guideline for scholars in the humanities who seek to work with professionals in other fields in order to enhance their research with digital tools.This Best Practices document ...
Buhe, Elizabeth
core  

Scholarly Metrics Baseline: A Survey of Faculty Knowledge, Use, and Opinion About Scholarly Metrics [PDF]

, 2017
This article presents the results of a faculty survey conducted at the University of Vermont during academic year 2014-2015. The survey asked faculty about: familiarity with scholarly metrics, metric seeking habits, help seeking habits, and the role of ...
DeSanto, Daniel, Nichols, Aaron
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Interdisciplinary Campus, Interdisciplinary World: Reshaping Higher Education for the 21st century [PDF]

, 2011
In recent years, interdisciplinary fields have increased in academia. Some, such as biomedical science and genomics, are pairings of disciplines that, through their combined knowledge, have created new fields with unique focuses.
Staff, Editorial
core   +1 more source

Reviewing, indicating, and counting books for modern research evaluation systems [PDF]

, 2018
In this chapter, we focus on the specialists who have helped to improve the conditions for book assessments in research evaluation exercises, with empirically based data and insights supporting their greater integration.
A Natowitz, A Nederhof, A Schubert, A Spink, A Weel Van der, A Zuccala, A Zuccala, A Zuccala, A Zuccala, A Zuccala, A Zuccala, A Zuccala, A Zuccala, A Zuccala, A Zuccala, AC Kors, AJ Nederhof, AJM Linmans, AV Rubio, B Cronin, B Cronin, B Flyvberg, B González-Pereira, B Hammarfelt, B Tillet, B Tillet, C Basili, C Beghtol, D Hicks, D Motta-Roth, D Torres-Salinas, D Torres-Salinas, D Torres-Salinas, D Torres-Salinas, D Torres-Salinas, DT Champion, E Archambault, E Garfield, E Garfield, E Garfield, E Garfield, E Giménez-Toledo, E Giménez-Toledo, E Giménez-Toledo, E Giménez-Toledo, EL Eisenstein, FT Verleysen, G Lewison, G Sivertsen, G Williams, H Regnery, H White, HD White, HF Moed, HF Moed, HF Moed, J Fry, J Gorraiz, J Gorraiz, J Guillory, J Hartley, J Mañana-Rodríguez, J Nicolaisen, J Serebnick, JB Thomson, JM Parker, JW Cortada, JW Thompson, K Kousha, K Kousha, K Kousha, K Kousha, K Kousha, K Kousha, KW Boyack, L Butler, L Butler, L Leydesdorff, L Leydesdorff, LA Coser, LE Riley, LM Chan, M Huang, M Mann, M Thelwall, MI Dorta González, N Glenn, P Dorta González, P Williams, P-S Chi, P-S Chi, RA Day, RP Smiraglia, S Fish, S Milojević, TCE Engels, TD Bilhartz, TLB Ossenblok, V Diodato, V Larivière, VE Hargrave, W Glänzel, W Glänzel, W Glänzel, WE Snizek, WE Snizek, Y Gingras, Y Lindholm-Romantschuk   +107 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Axiomatic Design and Design Thinking in Humanities and Social Sciences in the 21st Century

MATEC Web of Conferences, 2018
Since the Industrial Revolution (IR), science and technology have advanced at an ever-accelerating rate. In a mere 250 years since IR, advances in science and technology have changed nearly all aspects of humanity. Before IR, people and animals were used
Suh Nam Pyo
doaj   +1 more source