Results 71 to 80 of about 6,555 (219)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

A Lie Theoretic Proposal on Algorithms for Spherical Harmonic Lighting [PDF]

open access: yes, 2013
In this article (abstract of the presentation), we would like to provide a group theoretical background of spherical harmonics first, and using this, we propose a possible geometry preserving algebraic/efficient computing, which might accelerate the ...
Wakayama, Masato, 若山, 正人
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Random matrices, large deviations and reflected Brownian motion [PDF]

open access: yes
In this thesis we present results in large deviations theory, free probability and the theory of reflected Brownian motion. We study the large deviations behaviour of the block structure of a non-crossing partition chosen uniformly at random.
Ortmann, Janosch
core  

Sobre la acotación de la transformada de Hilbert en espacios de Lebesgue de la recta real [PDF]

open access: yes, 2020
[ES] La transformada de Hilbert es un ejemplo clásico de Integrales Singulares. El tema de Integrales Singulares tiene importantes conexiones con el estudio de las Series de Fourier, de las Ecuaciones Diferenciales Parciales y otras ramas de análisis y ...
Bonato, Giulia
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

An analytical, phenomenological and numerical study of geophysical and magnetohydrodynamic turbulence in two dimensions [PDF]

open access: yes, 2013
In this thesis I study a variety of two-dimensional turbulent systems using a mixed analytical, phenomenological and numerical approach. The systems under consideration are governed by the two-dimensional Navier-Stokes (2DNS), surface quasigeostrophic
Blackbourn, Luke A. K.
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

On fundamental sets of solutions of the equations of lateral motion, and the rapid calculation of general solutions [PDF]

open access: yes, 1945
The lateral motion of a symmetrical aeroplane slightly disturbed from steady flight is determined, to the first order of small quantities, by the solution of a system of six simultaneous linear differential equations with constant coefficients, in which ...
K. Mitchell
core  

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