Results 91 to 100 of about 490,864 (295)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Mechanical Engineering Students Win Big in Las Vegas | College of Engineering [PDF]
, 2017 Mechanical engineering students from Utah State University competed against 23 other teams and won 2nd place overall in the 2017 Human Powered Vehicle Challenge.https://digitalcommons.usu.edu/engineering_news/1209/thumbnail ...
USU College of Engineering
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Hierarchical controller for highly dynamic locomotion utilizing pattern modulation and impedance control : implementation on the MIT Cheetah robot [PDF]
, 2013 Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (pages 105-111).This thesis presents a hierarchical control algorithm for quadrupedal
Lee, Jongwoo, (Scientist in Mechanical Engineering) Massachusetts Institute of Technology
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Applied Sciences, 2019 Melt electrospinning writing has been emerged as a promising technique in the field of tissue engineering, with the capability of fabricating controllable and highly ordered complex three-dimensional geometries from a wide range of polymers.
Ferdows Afghah +3 more
doaj +1 more source
Caietele EchinoxThis study undertakes a critical investigation of the cinematic adaptation Mortal Engines (2018) directed by Christian Rivers, situating it within the broader theoretical and aesthetic framework of the steampunk genre. Tracing steampunk’s origins alongside its evolution into a fully realized visual mode, the study interrogates the film’s deployment of ...
openaire +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A hybrid computational and analytical model of irrigation drip emitters [PDF]
, 2017 Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2017.Cataloged from PDF version of thesis.Includes bibliographical references (pages 63-65).This thesis details a hybrid computational and analytical model to ...
Narain, Jaya, (Scientist in Mechanical Engineering) Massachusetts Institute of Technology
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source