Results 141 to 150 of about 1,990,739 (252)

Moderate-to-severe chronic spontaneous urticaria is associated with increased risk of immune-mediated diseases: A population-based study. [PDF]

PLoS One
Smart K, Ure A, Johnsen N, Aflatooni S, Cortes JA, Palma G, Nong Y, Borba AJ, Levins PC, Armstrong AW.   +9 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

How (not) to write about health equity. [PDF]

PLOS Glob Public Health
Koay A, Bowleg L, Lee PH, Burgess RA.
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Ensuring children's inclusion in the Bundibugyo Ebola response: Striving to do better this time. [PDF]

PLOS Glob Public Health
Kalmus Eliasz M, Adeyemi-Lawal M, D'Mello Guyett L, Manno D, Myango B, Reges P, Russell N.   +6 more
europepmc   +1 more source

Health Sciences Report (1997)

, 1997
UNIVERSITY OF UTAH THE APROBABLE LIFE OF trio C FROM THE EDITOR On these wintry days when the white landscape blurs into the cloudy horizon, we welcome warmth. In hospital offices, clinics and patient rooms though, we frequently take it for granted. Only

core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

First use of rapid ICT screening for Toxoplasma in pregnant women in Ethiopia: A multicenter study in Bahir Dar, Ethiopia. [PDF]

PLoS Negl Trop Dis
Gelaw YM, Dagnew GW, Sinishaw MA, Hiyaru T, Alene GD, Gangneux JP, Robert-Gangneux F.   +6 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Integration of the Integrated Emergency Surgical Officers (IESO) initiative within the health system: Perspectives of non-physician surgeons in Ethiopia's Tigray region. [PDF]

PLoS One
Teka H, Alemayehu M, Tequare MH, Berhe H, Haileeyesus HG, Nardos R.   +5 more
europepmc   +1 more source