Results 191 to 200 of about 1,868,350 (238)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Unveiling the hidden burden: Common mental disorders among women attending antenatal care in selected health facilities of Lusaka, Zambia. [PDF]

PLOS Ment Health
Jacobs C, Nkhowani J, Ngosa D, Shanaube K, Sandøy IF.   +4 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Determinants of HIV testing and oral PrEP uptake among youth at Malawi University of Business and Applied Sciences: A cross-sectional study employing the Health Belief Model. [PDF]

PLOS Glob Public Health
Mommertz JK, Kamanga M, Nyondo WM, Mapulanga P, Kumbani LC.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Predictive modeling in biology and medicine: Digital twins and multi-scale modeling. [PDF]

PLoS Comput Biol
Alber M, Smith A, Laubenbacher R, Merks RMH.   +3 more
europepmc   +1 more source

High-risk human papillomavirus prevalence and factors associated with testing positive in women living in Montserrat. [PDF]

PLOS Glob Public Health
Harris C, Skerritt-Flemming T, Hazel-Blake D, Maloney P, Daniel-Bourne K, Lee J, Barrasa A, Mosley O, Tirion A, Pae R, Greenaway-Duberry S, Manley P.   +11 more
europepmc   +1 more source

Uganda's cholera elimination journey in a cholera endemic region of Africa. [PDF]

PLOS Glob Public Health
Bwire G, Sack DA, Muruta A, Olaro C, Ocero JRA, Atwine D, Mwebesa HG, Ongole F, Kintu B, Nakinsige A, Immaculate A, Wabwire BA, Wanyenze RK, Debes AK, Orach CG.   +14 more
europepmc   +1 more source

Potential reasons for the decline of new HIV cases among people who inject drugs (PWID) in Kyrgyzstan. [PDF]

PLoS One
Moldokmatova A, Pan-Ngum W, Ariana P, Franco C, Aguas R, Zhumalieva C, Asangozhoeva Z, White L.   +7 more
europepmc   +1 more source

Use of naloxone by EMS for opioid-associated out-of-hospital cardiac arrest and associated patient-centered outcomes: A systematic review. [PDF]

PLoS One
Siddiqui H, Brouillette K, Walsh C, Cheskes S, Drennan IR, Keown-Stoneman CDG, Lin S, Mohindra R.   +7 more
europepmc   +1 more source