Results 91 to 100 of about 29,303,627 (284)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A Review of Generative Adversarial Networks (GANs) and Its Applications in a Wide Variety of Disciplines: From Medical to Remote Sensing

IEEE Access
We look into Generative Adversarial Network (GAN), its prevalent variants and applications in a number of sectors. GANs combine two neural networks that compete against one another using zero-sum game theory, allowing them to create much crisper and ...
Ankan Dash, Junyi Ye, Guiling Wang
doaj   +1 more source

The phase sensitivity of a fully quantum three-mode nonlinear interferometer

New Journal of Physics, 2018
We study a nonlinear interferometer consisting of two consecutive parametric amplifiers, where all three optical fields (pump, signal and idler) are treated quantum mechanically, allowing for pump depletion and other quantum phenomena. The interaction of
Jefferson Flórez, Enno Giese, Davor Curic, Lambert Giner, Robert W Boyd, Jeff S Lundeen   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Classification of algebraic function fields with class number one [PDF]

, 2015
In this paper we prove that there are exactly eight function fields, up to isomorphism, over finite fields with class number one and positive genus. This classification was already suggested, although not completely proved, in a previous work about this ...
MERCURI, PIETRO, STIRPE, CLAUDIO
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Data for: Nuclear genome shuffling increases recombinant protein expression in the chloroplast of Chlamydomonas reinhardtii

Supplemental data for "Nuclear genome shuffling significantly increases production of chloroplast-based recombinant protein in Chlamydomonas reinhardtii" by Fields et ...
Fields, F
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Dynamics and resonance fluorescence from a superconducting artificial atom doubly driven by quantized and classical fields

Physical Review Research
We report an experimental demonstration of resonance fluorescence in a two-level superconducting artificial atom under two driving fields coupled to a detuned cavity.
Xinhui Ruan, Jia-Heng Wang, Dong He, Pengtao Song, Shengyong Li, Qianchuan Zhao, L. M. Kuang, Jaw-Shen Tsai, Chang-Ling Zou, Jing Zhang, Dongning Zheng, O. V. Astafiev, Yu-xi Liu, Zhihui Peng   +13 more
doaj   +1 more source

Investigations into resistance in black-grass (Alopecurus myosuroides) in Baden-Württemberg and into herbicidal efficiency to reduce the risk of resistance developing

Julius-Kühn-Archiv, 2012
Suspicious samples of black-grass seeds from fields in Baden-Württemberg were tested in the greenhouse in 2008 to 2010 for their degree of resistance. The resistance to ACCase-inhibiting herbicides was widespread.
Gutjahr, Christoph, Hüsgen, Kerstin, Reitz, Tanja, Merz, Friedrich   +3 more
doaj   +1 more source