Results 161 to 170 of about 29,303,627 (284)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

The evaluation of citation distributions. [PDF]

open access: yes
This paper reviews a number of recent contributions that demonstrate that a blend of welfare economics and statistical analysis is useful in the evaluation of the citations received by scientific papers in the periodical literature.
Ruiz-Castillo, Javier
core  

Leveraging particle dynamics in force-fields for network packet routing. [PDF]

open access: yesPLoS One
Biswas S   +4 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Death certificate: Mrs. Cora Fields

open access: yes, 1917
This is a photograph of the death certificate for Mrs. Cora Fields, deceased on 1917-09-07, filed with the Arkansas Department of Health by the Ruebel Funeral Home in Little Rock.Transcribed.
Ruebel Funeral Home (Little Rock, Ark.)
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Death certificate: Fred Fields

open access: yes, 1917
This is a photograph of the death certificate for Fred Fields, deceased on 1917-12-24, filed with the Arkansas Department of Health by the Ruebel Funeral Home in Little Rock.Transcribed.
Ruebel Funeral Home (Little Rock, Ark.)
core  

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