Results 31 to 40 of about 2,511 (218)
The Representation of Time and Change in Mechanics [PDF]
, 2005 This paper is concerned with the representation of time and change in classical (i.e., non-quantum) physical theories. One of the main goals is to attempt to clarify the nature and scope of the so-called problem of time: a knot of technical and ...
Belot, Gordon
core
A comparison of two initialization methods in data assimilation [PDF]
, 1982 Two different initialization methods were developed and tested in global data assimilation experiments covering a five-day period. One method was based on the nonlinear normal mode initialization, and the other was based on the balance equation.
Barker, Edward Harrison
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Lavrentiev Phenomenon in Microstructure Theory
, 1996 A variational problem arising as a model in martensitic phase transformation including surface energy is studied. It explains the complex, multi-dimensional pattern of twin branching which is often observed in a martensitic phase near the austenite ...
Winter, M, Matthias Winter
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Detection of Subgingival Calculus by Optical Methods
, 2011 The central hypothesis of this thesis is that calculus can be identified based on its unique optical properties (reflection and fluorescence). Detection of subgingival calculus using conventional tactile senses has limited sensitivity and specificity ...
Fardad Shakibaie
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Shape optimization of pressurized air bearings
, 2002 Use of externally pressurized air bearings allows for the design of mechanical systems requiring extreme precision in positioning. One application is the fine control for the positioning of mirrors in large-scale optical telescopes.
Saintval, W. +7 more
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source