Results 51 to 60 of about 97,675,816 (255)
Numerical Methods in Civil Engineering, 2018 In this research, an efficient Galerkin Finite Volume Method (GFVM) along with the h– refinement adaptive process and post–processing error estimation analysis is presented for fracture analysis.
H. Rabbani-Zadeh +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Proceedings of the Congress on Numerical Methods in Engineering CMN 2022
, 2022 This book contains the Proceedings of the “Congress on Numerical Methods in Engineering (CMN 2022)” (https://congress.cimne.com/cmn2022), which took place from 12th to 14th September 2022 in Las Palmas de Gran Canaria, Spain, organized by the “Sociedad ...
core
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Efficient approximation of random fields for numerical applications [PDF]
, 2014 This article is dedicated to the rapid computation of separable expansions for the approximation of random fields. We consider approaches based on techniques from the approximation of non-local operators on the one hand and based on the pivoted Cholesky ...
Michael Peters +5 more
core +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Thermodynamics in solid mechanics: a commentary
, 2005 This commentary on thermodynamics in solid mechanics aims to provide an overview of the main concepts of thermodynamic processes as they apply to, and may be exploited for, studies in nonlinear solid mechanics.
Baker, Graham
core +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Hydrodynamic and solid residence time distribution in a circulating fluidized bed: experimental and 3D computational study [PDF]
, 2008 Vertical profiles of local pressure, horizontal profiles of net vertical solid mass flux, and residence time distributions (RTD) of the solid phase are experimentally assessed in the riser of a small scale cold Circulating Fluidized Bed of 9 m high ...
Simonin, Olivier +3 more
core +1 more source