Results 141 to 150 of about 1,770,157 (292)

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak   +9 more
wiley   +1 more source

Models for providing improved care in residential care homes: a thematic literature review [PDF]

open access: yes
This Annotated Bibliography is one output from a review of the available research evidence to support improved care in residential care homes as the needs of older people intensify. Key findings The review identified extremely little published evidence
Clay, Diane   +4 more
core  

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

open access: yesAdvanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu   +10 more
wiley   +1 more source

The Lived Experiences of Racism Among Indigenous Nursing Students Enrolled in a Canadian Baccalaureate Nursing Education Program

open access: yesQuality Advancement in Nursing Education
Rebecca Cameron, Patricia Gregory
doaj   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

open access: yesAdvanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv   +8 more
wiley   +1 more source

Copper Depletion Nanoparticles Potentiate Cancer Immunotherapy by Avoiding Innate and Adaptive Immune Resistance

open access: yesAdvanced Science, EarlyView.
A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou   +10 more
wiley   +1 more source

The Role of Artificial Intelligence in Medication Management for Older Adults: A Systematic Review

open access: yesAGING MEDICINE, EarlyView.
Artificial intelligence enhances medication management for older adults by improving adherence, personalizing treatment, and predicting risks. Despite benefits, challenges remain in usability, trust, ethics, and system integration. Successful adoption requires user‐centered design, ethical safeguards, and seamless healthcare integration to ensure safe,
Dipak Chandra Das   +9 more
wiley   +1 more source

Impact of Deprescribing Among Older Adults in Primary Care Settings: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesAGING MEDICINE, EarlyView.
Deprescribing interventions in primary care modestly reduce medication burden, patient falls, and hospitalisations among older adults, highlighting the value of medication reviews and collaborative care strategies. ABSTRACT Background Deprescribing is a systematic approach aimed at reducing the number of medications that are no longer beneficial or ...
Christina Malini Christopher   +6 more
wiley   +1 more source

Effects of instructional videos on the knowledge and labour practical skills of nursing students

open access: yesJournal of Health Science and Medical Research (JHSMR), 2008
The aims of this quasi-experimental research were to compare the students' knowledge of nursing practice before and after providing an instruction pack with videos, compare the knowledge of nursing practice between an experimental and a control group of ...
S Kala, S Youngwanichsate, S Chunuan
doaj  

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