Results 71 to 80 of about 22,563,111 (293)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Modeling student pathways in a physics bachelor’s degree program

Physical Review Physics Education Research, 2019
Physics education research (PER) has used quantitative modeling techniques to explore learning, affect, and other aspects of physics education. However, these studies have rarely examined the predictive output of the models, instead focusing on the ...
John M. Aiken, Rachel Henderson, Marcos D. Caballero   +2 more
doaj   +1 more source

Refined characterization of student perspectives on quantum physics [PDF]

, 2010
The perspectives of introductory classical physics students can often negatively influence how those students later interpret quantum phenomena when taking an introductory course in modern physics.
Charles Baily, Baily, Charles, Finkelstein, Noah D., Noah D. Finkelstein   +3 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Gender differences in self-efficacy states in high school physics

Physical Review Physics Education Research, 2019
Self-efficacy, the belief in one’s ability to succeed in learning tasks, predicts learning and success in education broadly and physics specifically. While self-efficacy increases for students in most introductory science and mathematics courses, self ...
Jayson M. Nissen
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Quantum mechanics principle and other physics principles involved in light and laser therapy

Journal of Cosmetic Medicine
Laser and light therapies have revolutionized the field of cosmetic medicine because of their ability to treat a range of dermatological conditions safely and effectively.
Cheuk Hung Lee, Kar Wai Alvin Lee, Kwin Wah Chan   +2 more
doaj   +1 more source

Notes on the historical conceptual streams for mathematics and physics teaching

Lietuvos Matematikos Rinkinys, 2013
Based on recent researches of mine concerning history and epistemology of sciences (physics and mathematics) one side and foundations of sciences within my physics and mathematics teaching other side, in this paper I briefly discuss and report the role ...
Raffaele Pisano
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source