Results 61 to 70 of about 1,586 (147)

A Model of Strategic Sustainable Investment

Mathematical Finance, EarlyView.
ABSTRACT We study a problem of optimal irreversible investment and emission reduction formulated as a nonzero‐sum dynamic game between an investor with environmental preferences and a firm. The game is set in continuous‐time on an infinite‐time horizon.
Tiziano De Angelis, Caio César Graciani Rodrigues, Peter Tankov   +2 more
wiley   +1 more source

Market Making With Fads, Informed, and Uninformed Traders

Mathematical Finance, EarlyView.
ABSTRACT We characterize the solution to a continuous‐time optimal liquidity provision problem in a market populated by informed and uninformed traders. In our model, the asset price exhibits fads —these are short‐term deviations from the fundamental value of the asset.
Emilio Barucci, Adrien Mathieu, Leandro Sánchez‐Betancourt   +2 more
wiley   +1 more source

Incretin‐Based Medications in Women and Reproduction: A Systematic Scoping Review and Consensus Guidelines for Clinical Practice

Obesity Reviews, EarlyView.
ABSTRACT Introduction Pregnancy concurrent with incretin‐based medications is contraindicated due to unknown risk of teratogenicity, as is breastfeeding. The aim of this systematic scoping review was to investigate potential risks and benefits of incretin‐based medications in relation to preconception, pregnancy, and postnatal health, and to propose ...
Kate Maslin, Jill Shawe, Sinead Blowers, Michael Ceulemans, Kathryn Hart, Sam Schoenmakers, Amihai Rottenstreich, Heather Hopper, Mojca Jensterle, Angela C. Flynn, Sarah Siegelaar, Annick Bogaerts, Isy Douek, Nicola Heslehurst, Dries Ceulemans, Tricia Tan, Johnathan Pinkney, Martin Whyte, Shahrad Taheri, Roland Devlieger   +19 more
wiley   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

Utility of local capillary supply indices: Insights from computational image‐based modelling

The Journal of Physiology, EarlyView.
Abstract figure legend Local capillary distribution and fibre geometry influence oxygen availability in skeletal muscle. Image‐based modelling of tissue PO2${{P}_{{{{\mathrm{O}}}_2}}}$ shows that area‐based measures of capillary supply – the local capillary density (LCDi) and local maximum diffusion distance (Dmax,i) – most accurately represent the ...
Abdullah A. Al‐Shammari, Roger W. P. Kissane, Ali Ashkanani, Ashraf Al Madhoun, Fahd Al‐Mulla, Eamonn A. Gaffney, Stuart Egginton   +6 more
wiley   +1 more source

Unveiling the role of the venous system in arterial hypertension: A computational study

The Journal of Physiology, EarlyView.
Abstract figure legend This abstract figure summarizes the principal findings of our computational analysis of hypertension. Model‐based results identify reduced venous compliance as a major determinant of elevated arterial pressure, second only to increased peripheral resistance.
Eleuterio F. Toro, Lucas O. Müller, Tonja W. Emans, Fiona D. McBryde, Julian F. R. Paton   +4 more
wiley   +1 more source

Electrodiffusion in cardiac intercalated disc nanostructures alters cell–cell action potential transmission via ephaptic coupling: A model study

The Journal of Physiology, EarlyView.
Abstract figure legend Ephaptic phenomena in a high‐resolution model of the cardiac intercalated disc. Meshed representation of a tortuous intercalated disc that was generated based on electron and super‐resolution microscopy data. Na+ channels (red) and gap junctions (green) are heterogeneously distributed, with additional regions of reduced ion ...
Ena Ivanovic, Marina Vannucci, Nicolae Moise, Seth H. Weinberg, Jan P. Kucera   +4 more
wiley   +1 more source

Inverse problems for semilinear elliptic PDE with a general nonlinearity a(x,u)$a(x,u)$

Transactions of the London Mathematical Society, Volume 13, Issue 1, December 2026.
Abstract This article studies the inverse problem of recovering a nonlinearity in an elliptic equation Δu+a(x,u)=0$\Delta u + a(x,u) = 0$ from boundary measurements of solutions. Previous results based on first‐order linearization achieve this under a sign condition on ∂ua(x,u)$\partial _u a(x,u)$, and results based on higher order linearization ...
David Johansson, Janne Nurminen, Mikko Salo   +2 more
wiley   +1 more source

A Posteriori Estimates For A Coupled Piezoelectric Model With Uncertain Data

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 3, September 2026.
ABSTRACT The paper is concerned with a coupled piezo‐electric problem with incompletely known coefficients of the elasticity tensor and two other tensors that define electric properties of the media. Due to this uncertainty, the problem possesses a set (cloud) of equally probable solutions instead of a unique solution.
S. Repin, T. Samrowski
wiley   +1 more source

Toward Robust Optimal Control of Chromatographic Separation Processes With Controlled Flow Reversal

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 3, September 2026.
ABSTRACT Column liquid chromatography is an important technique applied in the production of biopharmaceuticals, specifically for the separation of biological macromolecules such as proteins. When setting up process conditions, it is crucial that the purity of the product is sufficiently high, even in the presence of perturbations in the process ...
Dominik H. Cebulla, Christian Kirches, Andreas Potschka   +2 more
wiley   +1 more source