Results 131 to 140 of about 74,836 (307)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Other/the other: Tradition of reducing the other to an other
Theoria, Beograd, 2009 Modern thought essentially reduced The Other to that which is mere other. The result was knowledge in function of power and domination. Nevertheless, one should seek for solution in idea of ethical transcendence, a concept that possesses highly emancipative potentials towards a world with more justice and liberty.
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A call to loyalty: women’s bodies, playgrounds and battlefields [PDF]
, 2017 Este artículo muestra cómo los argumentos feministas utilizados por discursos de derecha populistas y xenofóbicos contribuyen a la neutralización del feminismo en el discurso público europeo, la libertad de la mujer se invoca para fines que tienen poco ...
Spini, Debora
core +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Review of Significant Other. Staging the American in China by Claire Conceison [PDF]
, 2008 Ferrari, Rossella
core +1 more source
Memories of Home: Reading the Bedouin In Arab American Literature [PDF]
, 2008 In an urban neighborhood with a large Jewish population near my home, there is an Arabic restaurant. Name, menu and ownership mark its ethnic identification, yet its politics are otherwise obscured.
Wardi, Anissa J., Wardi-Zonna, Katherine
core +2 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source