Results 51 to 60 of about 1,791 (253)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Northern Cypriot Dream - Turkish Immigration 1974-1980 [PDF]

open access: yes, 2014
After the division of Cyprus in 1974 into a Greek Cypriot south and a Turkish Cypriot north, approximately 30,000 immigrants from Turkey moved to north Cyprus. The period between 1974 and 1980 is the time during which these immigrants arrived in northern
Jensehaugen, Helge
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Sosyolojik Düşüncede Avrupa-merkezcilik, Ötekileştirme ve Oryantalist Söylem Üzerine Post-kolonyal bir Okuma ve Eleştirisi

open access: yesULUM, 2018
Modernite, uzun bir zamandır tüm dünyada, Avrupa-merkezci bir ideolojiyle suç ortaklığı yapmasına ve özünde barındırdığı çelişkilerin bağdaşmazlığına rağmen, bilgi üretimi ve disiplinlerin teorik çerçevesini belirlemede hâkim paradigma olmayı ...
İrfan Kaya
doaj  

A Cosmopolitan response to the 'war on terror' [PDF]

open access: yes, 2019
This article explores the relevance and the significance of cosmopolitanism as an approach to understanding the ‘war on terror’. The article details how cosmopolitanism affords a perspective through which it is possible to critique and deconstruct the ...
Ahmed, S., Ahmed, S.
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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