Results 81 to 90 of about 28,980 (179)

A Multicenter Phase II Trial of Nimustine Hydrochloride Administered via Convection‐Enhanced Delivery in Children With DIPG

open access: yesCancer Science, EarlyView.
The efficacy of the CED of nimustine hydrochloride in pediatric DIPG was evaluated. One‐year survival rate from the start of radiotherapy was 60%. The treatment strategy demonstrated potential efficacy. ABSTRACT Diffuse intrinsic pontine glioma (DIPG) is a very challenging‐to‐treat pediatric malignant tumor, with a median survival time of < 12 months ...
Ryuta Saito   +13 more
wiley   +1 more source

A Cryptic CBFB Deletion–Inversion Expands the Mutational Spectrum of Variants Associated With Cleidocranial Dysplasia

open access: yesClinical Genetics, EarlyView.
Following clinical review of a 100 000 Genomes Project family with genetically‐unsolved CCD, we manually inspected read‐alignments and identified a deletion‐inversion‐deletion that removes the first two exons of CBFB. This cryptic variant comprised deletions of 1310/1935bp, was undetectable by array‐CGH and was likely mediated by palindromic AluSx ...
Alistair T. Pagnamenta   +6 more
wiley   +1 more source

Genotypic and Phenotypic Characterization of Seven Individuals With Predicted Bone Morphogenetic Protein 2 (BMP2) Haploinsufficiency

open access: yesClinical Genetics, EarlyView.
BMP2 haploinsufficiency is known to be associated with short stature, skeletal malformations, specific craniofacial traits and cardiac malformations. This study including individuals with predicted BMP2 haploinsufficiency provides additional insight regarding less established and sometimes controversial phenotypes such as degree of developmental delay,
Elin Stavrén‐Eriksson   +5 more
wiley   +1 more source

"COMFORTER" OTITIS MEDIA. [PDF]

open access: green, 1911
Eric Pritchard
openalex   +1 more source

Systematic Review and Meta‐Analysis of Audiometric Parameters for Assistive Hearing Technology for Adults and Children With Tympanic Membrane Perforation

open access: yesClinical Otolaryngology, EarlyView.
ABSTRACT Introduction Tympanic membrane perforation can cause hearing impairment with detrimental effects on communication and quality of life, and is a problem affecting an estimated 250 million people. To date, there is little analysis to inform public policy on options for assistive hearing technology rehabilitation in this group.
Thomas Hampton   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy