Results 1 to 10 of about 61,657 (247)

Silencing Nrf2 attenuates chronic suppurative otitis media by inhibiting pro-inflammatory cytokine secretion through up-regulating TLR4

Innate Immunity, 2021
Compromised TLR-mediated chronic inflammation contributes to bacterial infection-caused chronic suppurative otitis media, but the mechanisms are unclear.
Abulajiang Tuoheti, Xingzhi Gu, Xiuqin Cheng, Hua Zhang   +3 more
doaj   +2 more sources

Prevalence and clinico-bacteriological aspects of chronic suppurative otitis media at the Renaissance University Hospital in N'Djamena, Chad

The Egyptian Journal of Otolaryngology, 2023
Background Chronic suppurative otitis media is a major cause of hearing impairment and morbidity in poor socioeconomic developing countries. Objectives To determine the prevalence of chronic suppurative otitis media in a tertiary care hospital and to ...
Aboubakar Assidick Taoussi, Mahamat Seïd Mahamat Malloum, Yusra Aboulbachar Ali   +2 more
doaj   +2 more sources

Day-case management of chronic suppurative otitis media with cholesteatoma with canal wall down technique surgery: long-term follow-up [PDF]

Audiology Research, 2017
The overall number of day-case otologic surgery cases is increasing; however, there is limited experience about performing canal wall down tympanoplasty in patients with chronic suppurative otitis media with cholesteatoma in this setting.
Giovanni Ralli, Giuseppe Nola, Alberto Taglioni, Michele Grasso, Massimo Ralli   +4 more
doaj   +4 more sources

The causal relationship between obstructive sleep apnea and otitis media: a bidirectional Mendelian randomization study [PDF]

Experimental Biology and Medicine
Obstructive sleep apnea (OSA) is manifested as periodic collapse of the upper airway during sleep. Otitis media is a spectrum of infectious and inflammatory diseases involving the middle ear. In this study, we sought to determine the causal effect of OSA
Ruixin Guo, Yifan Zhang, Yijie Chen, Wenqi Sha, Wanyi Kou, Chensi Xu, Yuran Lei, Ningrui Zhang, Liu Yang, Yun Guo, Huihui Zhang, Zhenghui Wang, Zhenghui Wang   +12 more
doaj   +2 more sources

Case Report: Management of Chronic Supurative Otitis Media Cholesteatoma Type with Recurrent Brain Abscess Complication

Journal of Agromedicine and Medical Sciences (AMS), 2022
Introduction: Chronic suppurative otitis media is broadly defined as chronic inflammation that involved mucose of middle ear and mastoid air cells.
Khairani Ayunanda Ikhlas, Yan Edward
doaj   +1 more source

Chronic Suppurative Otitis Media: A Comprehensive Review of Epidemiology, Pathogenesis, Microbiology, and Complications

Cureus, 2023
Otitis media is a significant contributor to healthcare visits and the prescription of drugs. Its associated complications and consequences pose the primary factors for preventable hearing impairment, especially in developing nations. Chronic suppurative
Mihika Khairkar, Prasad Deshmukh, H. Maity, V. Deotale   +3 more
semanticscholar   +1 more source

Risk factors associated with the development of chronic suppurative otitis media in children: Systematic review and meta‐analysis

Clinical Otolaryngology, 2023
Chronic suppurative otitis media (CSOM) is defined as persistent discharge through a tympanic membrane perforation for greater than 2 weeks. It is associated with a significant disease burden, including hearing loss, and reducing its incidence could ...
E. Heward, H. Saeed, Sebastian Bate, Azita Rajai, John Molloy, R. Isba, Darren M Ashcroft, A. D. Hay, Jaya R Nichani, I. Bruce   +9 more
semanticscholar   +1 more source

Chronic suppurative otitis media causes macrophage-associated sensorineural hearing loss

Journal of Neuroinflammation, 2022
Background Chronic suppurative otitis media (CSOM) is the most common cause of permanent hearing loss in children in the developing world. A large component of the permanent hearing loss is sensory in nature and our understanding of the mechanism of this
A. Xia, Anthony Thai, Z. Cao, Xiaohua Chen, J. Chen, Brian Bacacao, L. Bekale, Viktoria Schiel, P. L. Bollyky, P. S. Maria   +9 more
semanticscholar   +1 more source

Management evaluation of patients with chronic suppurative otitis media: A retrospective study

Annals of Medicine and Surgery, 2021
Background Chronic suppurative otitis media (CSOM) is a chronic infection of the middle ear with perforation of the tympanic membrane and secrete from the ear more for than two months, either continuously or intermittently.
Sally Mahdiani, Lina Lasminingrum, Denis Anugrah   +2 more
semanticscholar   +1 more source

Topical versus systemic antibiotics for chronic suppurative otitis media.

Cochrane Database of Systematic Reviews, 2021
BACKGROUND Chronic suppurative otitis media (CSOM), sometimes referred to as chronic otitis media (COM), is a chronic inflammation and often polymicrobial infection (involving more than one micro-organism) of the middle ear and mastoid cavity ...
L. Chong, K. Head, K. Webster, J. Daw, P. Richmond, Tom Snelling, M. Bhutta, A. Schilder, M. Burton, Christopher G. Brennan-Jones   +9 more
semanticscholar   +1 more source