Results 31 to 40 of about 174,977 (242)
Advanced Science, EarlyView.A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun +15 more
wiley +1 more source
Corticosteroid use in otolaryngology: current considerations during the COVID-19 era [PDF]
, 2021 Objective: To offer pragmatic, evidence-informed advice on administering corticosteroids in otolaryngology during the coronavirus disease 2019 (COVID-19) pandemic, considering therapeutic efficacy, potential adverse effects, susceptibility to COVID-19 ...
Alexander T. Hillel +29 more
core +1 more source
Advanced Science, EarlyView.ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su +4 more
wiley +1 more source
The Role of Fine Needle Aspiration Cytology (FNAC) in the Management of Solitary Thyroid Nodules.
Khyber Medical University Journal, 2011 Objective:To determine the sensitivity, specificity and diagnostic accuracy of fine needle aspiration cytology in the management of solitary thyroid nodule.
Khurshid Anwar +2 more
doaj
Children, 2020 Parental attitudes regarding pain interventions and perceptions of their child’s pain intensity likely influence the decision to administer postoperative analgesics. Our study examined the impact of daily fluctuations in child pain intensity and parental
Jaclyn Lee +9 more
doaj +1 more source
Laryngoscope Investigative Otolaryngology, 2023 Objective To compare the workplace experience of European and U.S. members of the otolaryngology community. Methods European and U.S. otolaryngologists‐head and neck surgeons (OTO‐HNS) were surveyed through three otorhinolaryngological societies.
H. Steven Sims +2 more
doaj +1 more source
Advanced Science, EarlyView.A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang +4 more
wiley +1 more source
Promoting ENT‐erest: Evaluating the Effect of Early, Focused Exposure to Otolaryngology
OTO OpenObjective Exposure to otolaryngology throughout medical school is variable, with the majority of students receiving their first exposure in clerkships.
Makayla R. Matthews +4 more
doaj +1 more source
Nasal Foreign Body, Dislodged and Lost – Can the Adenoids Help? [PDF]
Journal of Clinical and Diagnostic Research, 2015 Foreign body in the nasal cavity is one of the most common paediatric otolaryngology emergencies and needs to be promptly addressed. The incidence of nasal foreign body getting dislodged secondary to unsuccessful attempts to take it out is quite high ...
Arijit Jotdar +2 more
doaj +1 more source
Advanced Science, EarlyView.In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang +19 more
wiley +1 more source