Results 21 to 30 of about 2,111,672 (212)

Brain response in asthma: the role of “lung-brain” axis mediated by neuroimmune crosstalk

Frontiers in Immunology, 2023
In addition to typical respiratory symptoms, patients with asthma are frequently accompanied by cognitive decline, mood disorders (anxiety and depression), sleep disorders, olfactory disorders, and other brain response manifestations, all of which worsen
Yao Wang, Yao Wang, Yao Wang, Ya-Kui Mou, Ya-Kui Mou, Ya-Kui Mou, Han-Rui Wang, Han-Rui Wang, Han-Rui Wang, Xiao-Yu Song, Xiao-Yu Song, Xiao-Yu Song, Shi-Zhuang Wei, Shi-Zhuang Wei, Shi-Zhuang Wei, Chao Ren, Chao Ren, Chao Ren, Chao Ren, Chao Ren, Xi-Cheng Song, Xi-Cheng Song, Xi-Cheng Song, Xi-Cheng Song   +23 more
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Microbial metabolites are involved in tumorigenesis and development by regulating immune responses

Frontiers in Immunology, 2023
The human microbiota is symbiotic with the host and can create a variety of metabolites. Under normal conditions, microbial metabolites can regulate host immune function and eliminate abnormal cells in a timely manner. However, when metabolite production
Jiahui Liu, Jiahui Liu, Jiahui Liu, Ruxian Tian, Ruxian Tian, Ruxian Tian, Caiyu Sun, Caiyu Sun, Caiyu Sun, Ying Guo, Ying Guo, Ying Guo, Lei Dong, Lei Dong, Lei Dong, Yumei Li, Yumei Li, Yumei Li, Xicheng Song, Xicheng Song, Xicheng Song   +20 more
doaj   +1 more source

Phase Separation Drives Pathological Aggregation in Neurodegenerative Diseases: A 15-Year Bibliometric Landscape (2009-2024). [PDF]

Ann N Y Acad Sci
This 15‐year bibliometric study (2009–2024) characterizes the global landscape of liquid–liquid phase separation (LLPS) in neurodegenerative diseases. We delineate the field's evolution from fundamental biophysics to clinical translation, emphasizing the liquid‐to‐solid transition of proteins like TDP‐43, tau, and α‐synuclein.
Zhang C, Chen S, Zhao H, Wang Y, Zhou L, Fan H, Sun Y.   +6 more
europepmc   +2 more sources

Tumor necrosis factor-α mediated inflammation versus apoptosis in age-related hearing loss

Frontiers in Aging Neuroscience, 2022
An almost universal phenomenon occurring during aging is a state of chronic, low-grade, sterile inflammation. Inflammation is a crucial contributor to various age-related pathologies and natural processes in aging tissues. Tumor necrosis factor-α (TNF-α),
Ting Wu, Ting Wu, Jiamin Zhou, Jiamin Zhou, Jingjing Qiu, Jingjing Qiu, Yuwan Song, Yuwan Song, Wentao Guo, Wentao Guo, Limei Cui, Limei Cui, Xicheng Song, Xicheng Song, Yan Sun, Yan Sun   +15 more
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Identification of a lncRNA AC011511.5- Mediated Competitive Endogenous RNA Network Involved in the Pathogenesis of Allergic Rhinitis

Frontiers in Genetics, 2022
LncRNA-miRNA-mRNA competing endogenous RNA (ceRNA) networks are thought to be involved in regulating the development of various inflammatory diseases. Up to now, the mechanism of such a network in allergic rhinitis (AR) remains unclear.
Yujuan Yang, Yujuan Yang, Qi Sun, Qi Sun, Jing Guo, Jing Guo, Zhen Liu, Zhen Liu, Jianwei Wang, Jianwei Wang, Yao Yao, Yao Yao, Pengyi Yu, Pengyi Yu, Jiayu Cao, Jiayu Cao, Yu Zhang, Yu Zhang, Xicheng Song, Xicheng Song   +19 more
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Case Report: Two cases of survival after complete transection of the left common carotid artery

Frontiers in Surgery, 2023
Penetrating carotid artery traumas are rare yet fatal injuries with a high rate of mortality, and survivors may live with neurological sequelae. Of all the types of penetrating carotid artery traumas, the total transection of the common carotid artery ...
Xin Yang, Xin Yang, Zhonglu Liu, Zhonglu Liu, Qi Sun, Qi Sun, Yakui Mou, Yakui Mou, Chuanliang Jia, Chuanliang Jia, Wenbin Zhang, Wenbin Zhang, Fei Song, Fei Song, Wen Li, Hua Zhang, Hua Zhang, Xicheng Song, Xicheng Song   +18 more
doaj   +1 more source

Network pharmacology analysis and experimental verification reveal the mechanism of the traditional Chinese medicine YU-Pingfeng San alleviating allergic rhinitis inflammatory responses

Frontiers in Plant Science, 2022
YU-Pingfeng San (YPFS) can regulate inflammatory response to alleviate the symptoms of nasal congestion and runny rose in allergic rhinitis (AR). However, the mechanism of action remains unclear.
Zhen Liu, Zhen Liu, Qi Sun, Qi Sun, Xinyue Liu, Xinyue Liu, Zheying Song, Zheying Song, Zheying Song, Fei Song, Fei Song, Fei Song, Congxian Lu, Congxian Lu, Yu Zhang, Yu Zhang, Xicheng Song, Xicheng Song, Yujuan Yang, Yujuan Yang, Yumei Li, Yumei Li   +21 more
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Subcutaneous emphysema with pneumomediastinum after elective tonsillectomy - Case study

Otolaryngology Case Reports, 2021
Tonsillectomy is a common operation in otorhinolaryngology with subcutaneous emphysema with pneumomediastinum being an uncommon, nevertheless, potentially life-threatening complication.
Dimitrios Paouris, Samuel Kunzo, Irina Šebová   +2 more
doaj   +1 more source

Identification and Validation of 17-lncRNA Related to Regulatory T Cell Heterogeneity as a Prognostic Signature for Head and Neck Squamous Cell Carcinoma

Frontiers in Immunology, 2021
Successful eradication of tumors by the immune system depends on generation of antigen-specific T cells that migrate to tumor sites and kill cancerous cells. However, presence of suppressive Treg populations inside tumor microenvironment hinders effector
Qi Sun, Qi Sun, Yumei Li, Yumei Li, Xin Yang, Xin Yang, Xinxin Wu, Xinxin Wu, Zhen Liu, Zhen Liu, Yakui Mou, Yakui Mou, Xicheng Song, Xicheng Song   +13 more
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Epithelial YPEL3 Modulates CD8⁺ T-Cell Infiltration and Tumor Progression Through CREB1-CXCL16 Signaling in HNSCC. [PDF]

Cancer Sci
YPEL3 functions as a tumor suppressor in HNSCC by inhibiting tumor progression and promoting apoptosis. Mechanistically, it enhances epithelial–immune crosstalk through the CREB1‐mediated CXCL16–CXCR6 axis, facilitating CD8+ T‐cell infiltration and highlighting its potential as a prognostic biomarker and immunotherapy target.
Li Y, Li Y, Sun C, Lu C, Chen G, Zhou T, Zhang B, Song X.   +7 more
europepmc   +2 more sources