Results 61 to 70 of about 2,243 (214)

Oncolytic Therapy: Delivery System and New Therapeutic Strategies for Cancer

MedComm, Volume 7, Issue 4, April 2026.
This review summarizes recent advances in nanoparticle‐ and cell‐mediated OVs delivery strategies that improve biodistribution and tumor targeting while limiting immune clearance. It also examines combination approaches that enhance therapeutic efficacy through tumor microenvironment modulation or immune activation, thereby overcoming immunosuppression
Sikan Jin, Yi Zhang, Ziling Zhou, Yaqi Zhang, Ting Yu, Rui Xu, Lin Xu, Jidong Zhang, Longze Zhang, Shan Yang, Xianyao Wang   +10 more
wiley   +1 more source

Copeptin for risk stratification in non-traumatic headache in the emergency setting: a prospective multicenter observational cohort study [PDF]

, 2017
In the emergency setting, non-traumatic headache is a benign symptom in 80% of cases, but serious underlying conditions need to be ruled out. Copeptin improves risk stratification in several acute diseases.
A Torres, AJ Vickers, Andreas Huber, B Muller, Beat Müller, Bettina Winzeler, BJ Blyth, BW Friedman, C Zweifel, Claudine Angela Blum, CM Forcelini, CM Kosinski, Cornelia Mueller, D Grimaldi, D Holle, DC Buse, DP Breen, E Elm von, E Loder, IE Widmer, JA Hanley, Janina Tepperberg, JJ Egea-Guerrero, Katharina Haaf, Katharina Timper, Krassen Nedeltchev, LB Morgenstern, M Katan, M Katan, M Katan, M Katan, M Ramirez-Lassepas, M Teepker, Margareth Amort, MB Jensen, Mira Katan, Mirjam Christ-Crain, MR Ananda-Rajah, NG Morgenthaler, NG Morgenthaler, Nicole Nigro, P Cortelli, P Durham, P L’Abate, P Schuetz, Peter Stephan Sándor, PG Charles, Philipp Schuetz, R Meng, R Riquelme, R Seligman, RA Marlow, RB Lipton, RJ Stevenson, Roland Bingisser, S Aliberti, S Guldiken, S Kruger, SH Ang, Silke Biethahn, T Locker, T Reichlin, TE Locker, Timo Kahles, U Arulmani   +64 more
core   +2 more sources

Biomarkers & Survival in Head and Neck Squamous Cell Carcinoma: A Systematic Review & Meta‐Analysis

OTO Open, Volume 10, Issue 2, April-June 2026.
Abstract Objective EGFR, cyclin D1, and Bcl‐2 are proteins involved in different stages of tumorigenesis which have all been associated with poor prognosis in head and neck squamous cell carcinoma (HNSCC). In this systematic review and meta‐analysis, we aim to measure the association of each protein with survival in HNSCC.
Jesse Siegel, William Adams, Kent Tadokoro, Veronica Drozdowski‐Nuccio, Carol Bier‐Laning   +4 more
wiley   +1 more source

The role and regulatory mechanism of lysosome associated protein transmembrane 4β in tumors

Frontiers in Oncology
The oncogene LAPTM4B (encoding lysosome-associated protein transmembrane-4β), first cloned in hepatocellular carcinoma cells, is located on chromosome 8q22.1 and encodes two isoforms, LAPTM4B-35 and LAPTM4B-24.
Yuteng Yang, Yuteng Yang, Yuteng Yang, Yuteng Yang, Yuteng Yang, Yumei Li, Yumei Li, Yumei Li, Yumei Li, Yaqi Wang, Yaqi Wang, Yaqi Wang, Yaqi Wang, Xi Chen, Xi Chen, Xi Chen, Xi Chen, Yisong Yao, Yisong Yao, Yisong Yao, Yisong Yao, Dongxian Li, Dongxian Li, Dongxian Li, Dongxian Li, Guohua Yu, Guohua Yu, Guohua Yu, Guohua Yu, Xicheng Song, Xicheng Song, Xicheng Song, Xicheng Song   +32 more
doaj   +1 more source

Computed Tomography-Based Radiomics Model to Predict Central Cervical Lymph Node Metastases in Papillary Thyroid Carcinoma: A Multicenter Study

Frontiers in Endocrinology, 2021
ObjectivesThis study aimed to develop a computed tomography (CT)-based radiomics model to predict central lymph node metastases (CLNM) preoperatively in patients with papillary thyroid carcinoma (PTC).MethodsIn this retrospective study, 678 patients with
Jingjing Li, Jingjing Li, Xinxin Wu, Ning Mao, Ning Mao, Ning Mao, Guibin Zheng, Haicheng Zhang, Yakui Mou, Yakui Mou, Chuanliang Jia, Chuanliang Jia, Chuanliang Jia, Jia Mi, Xicheng Song, Xicheng Song, Xicheng Song   +16 more
doaj   +1 more source

An Analysis of Clinical Questions Asked at Professor Rounds: A Ten-Year Review of Topics [PDF]

, 2014
Questions asked at residents’ educational conferences can be valuable catalysts for learning. Although finding answers to these queries is the ultimate goal, the topics of these questions themselves can be equally instructive.
Bianchi, Nancy A.
core   +1 more source

Incidence of lymph node metastases after piecemeal laser-surgical and en bloc cold steel resection of auricular VX2 carcinoma. A comparative study. [PDF]

, 2005
The CO2 laser surgery has become a widely used clinical treatment in otorhinolaryngology. In advanced neoplastic disease of the head and neck it is often difficult and even impossible to expose well the whole tumor through the surgical laryngoscope.
Sapundzhiev, Nikolay, Werner, J.A. (Prof. Dr.)   +1 more
core   +1 more source

Clinical Diagnostics After Failed Hearing Screening in People With Intellectual Disabilities Do Not Often Take Place

Journal of Intellectual Disability Research, Volume 70, Issue 4, Page 384-394, April 2026.
ABSTRACT Background Individuals with intellectual disabilities are at higher risk of undiagnosed or inadequately treated hearing loss. This situation requires easily accessible hearing screening, diagnostics and intervention programmes in the living environment, i.e., in nurseries, schools, workplaces and homes.
Anna Wiegand, Philipp Mathmann, Susanne Wasmuth, Lukas Prein, Ross Parfitt, Martin Scharpenberg, Vincent Jankovic, Katharina Schwarze, Anja Neumann, Karolin Schäfer, Christian Speckemeier, Sven Baessler, Sarah Schlierenkamp, Sandra Diekmann, Nicole Stuhrmann, Ruth Lang‐Roth, Muhittin Demir, Werner Brannath, Awa Naghipour, Susanna Marie Zielonkowski, Anna Sophia Schwalen, Corinna Gietmann, Katrin Neumann   +22 more
wiley   +1 more source

Which asthma patients should get the pneumococcal vaccine? [PDF]

, 2009
Adults between the ages of 19 and 64 years who have chronic lung disease, including asthma, should get the vaccine, as should all patients 65 years and older (strength of recommendation [SOR]: C, consensus guide-lines).
Edgerton, Lisa, Harris, John Brock, Stafford, Karen   +2 more
core  

Critical Evaluation of the Impact of COVID‐19 Pandemic on Child Health and Wellbeing and Suggested Preparedness for Future Pandemics–A Narrative Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims The immediate and long‐term effects of COVID‐19 pandemic on the children go beyond just being a viral infection. A child's mental health and psychological issues like irritability, anxiety, sadness, non‐attentiveness, attention deficit and hyperactive disorder needed evaluation.
Ranjan K. Mohapatra, Ashish K. Sarangi, Gurudutta Pattnaik, Puneet K. Singh, Rasmita Dash, Venkataramana Kandi, L. V. Simhachalam Kutikuppala, Rudra Narayan Sahoo, Snehasish Mishra, Anita Mishra, Sourya Subhra Nasker, Sasmita Nayak, Hayam A. Alrasheed, Nawal A. Al Kaabi, Amer Alshengeti, Altaf A. Abdulkhaliq, Ali A. Rabaan, Maha F. Al‐Subaie, Saad Alhumaid, Kuldeep Dhama, Md. Kudrat‐E‐Zahan   +20 more
wiley   +1 more source