Results 161 to 170 of about 96,741 (247)

AKT, ATR, and Notch Inhibitors Radiosensitize a Preclinical Model of Adenoid Cystic Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Adenoid Cystic Carcinoma (ACC) is a rare and lethal type of head and neck cancer. Standard therapy involves surgery followed by radiation therapy. The majority of ACC has MYB overexpression and MYB‐NFIB gene fusions, while Notch mutations are associated with aggressive behavior.
Shivani Thoidingjam   +10 more
wiley   +1 more source

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik   +6 more
wiley   +1 more source

Toward Dynamic and De-escalated Care: Insights from the ATA 2025 DTC Guidelines. [PDF]

open access: yesTurk Arch Otorhinolaryngol
Bayram A   +2 more
europepmc   +1 more source

Health System Factors in Head and Neck Cancer Diagnosis: A HEADSpAcE Consortium Qualitative Study in Glasgow and Montevideo

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Head and neck cancer (HNC) is a devastating diagnosis, with advanced‐stage disease leading to poorer outcomes. This qualitative study aimed to identify health system factors associated with stage of HNC diagnosis. Methods Qualitative semistructured interviews with HNC patients and clinicians were undertaken in two purposively ...
Grant Creaney   +196 more
wiley   +1 more source

Computer‐Aided Diagnosis in the Evaluation of Thyroid Nodules: A Study of Intra‐ And Inter‐Rater Reliability and Agreement

open access: yesHead &Neck, EarlyView.
ABSTRACT Objective To evaluate the intra‐ and inter‐rater reliability of a computer‐aided diagnosis system applied to thyroid nodule assessment. Methods This prospective, single‐center study included 150 thyroid nodules evaluated by two physicians at two time points, 90 days apart.
Leonardo de Souza Piber   +3 more
wiley   +1 more source

Chinese Guidelines for the Diagnosis and Surgical Treatment of Adult Obstructive Sleep Apnea (2024). [PDF]

open access: yesWorld J Otorhinolaryngol Head Neck Surg
Working Group of Guideline for the Diagnosis and Surgical Treatment of Adult OSA   +7 more
europepmc   +1 more source

Intensive Swallowing Rehabilitation for Head and Neck Cancer Survivors With Chronic Dysphagia: Outcomes From a Prospective Multicentre Cohort Study With 6‐Month Follow‐Up

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Chronic dysphagia persists in some head and neck cancer (HNC) survivors despite preventive exercises, negatively impacting quality of life. Evidence for effective rehabilitation strategies remains limited. Methods This prospective cohort study included 34 HNC survivors (≥ 1 year post‐treatment) who completed a 3‐week intensive ...
J. I. Oldenbeuving   +3 more
wiley   +1 more source

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