Results 21 to 30 of about 6,077 (171)
Unraveling the dangerous duet between cancer cell plasticity and drug resistance
Abstract Cancer cell plasticity is the ability of tumor cells to switch phenotypes and is one of the predominant requisites of cancer cells capable of undergoing metastasis. Cancer cell plasticity is also recognized as one of the major contributors to intratumoral heterogeneity, a critical factor underlying the progression of malignant tumors, which is
Namrata Chatterjee +4 more
wiley +1 more source
Deiscência do canal semicircular superior – Imitador Otológico
Objetivos: identificar características clínicas comuns em doentes com deiscência do canal semicircular superior (DCSS) no sentido de aumentar a suspeita diagnóstica desta entidade clínica. Material e Métodos: realizou-se uma análise retrospetiva entre
André Carção +5 more
doaj +1 more source
This study aimed to assess the impact of coronavirus disease‐19 lockdowns on allergic rhinitis (AR) symptoms reported by the patients treated with immunotherapy at two allergy referral centers in Colombia. Up to 38.4% of the AR patients reported that their symptoms got worse during lockdowns, probably due to higher exposure to indoor AR allergens and ...
Lucia C. Pérez‐Herrera +5 more
wiley +1 more source
Melanoma nasossinusal: Um estudo retrospectivo
Objetivo: Descrever o curso clínico, tratamento e prognóstico de doentes identificados com melanoma nasossinusal num hospital oncológico de referência. Desenho do Estudo: Estudo retrospectivo. Material e Métodos: Revisão dos processos clínicos dos
Ana Campos +7 more
doaj +1 more source
Abstract Background After internal carotid artery (ICA) injury during endoscopic skull base surgery, the majority of patients undergo ICA embolization or stenting to treat active extravasation or pseudoaneurysm development. However, management practices when embolization or stenting is not required have not been well described.
Nyall R. London Jr +20 more
wiley +1 more source
Perda aguda de audição em doentes com infecção por SARS-CoV-2
Objectivos: Avaliar a relação entre a infecção pelo vírus SARS-CoV-2 e a ocorrência de surdez súbita. Desenho do Estudo: Caso clínico e revisão da literatura Material e Métodos: Descrição de 2 casos clínicos de hipoacusia neurosensorial de ...
Filipa Ruas Morgado +6 more
doaj +1 more source
Mechanistic insights into the heterogeneous response to anti‐VEGF treatment in tumors
Abstract Vascular endothelial growth factor (VEGF) is a strong promoter of angiogenesis in tumors, and anti‐VEGF treatment, such as a humanized antibody to VEGF, is clinically used as a monotherapy or in combination with chemotherapy to treat cancer patients. However, this approach is not effective in all patients or cancer types.
Ding Li, Stacey D. Finley
wiley +1 more source
Worldwide comparison of treatment guidelines for sore throat
Abstract Introduction Sore throat (acute pharyngitis) is globally one of the most frequent reasons for seeking healthcare. Its etiology is mostly viral. In 15%‐30% of cases, group A streptococci (GAS) are detected, which may cause acute rheumatic fever.
Graça Coutinho +4 more
wiley +1 more source
The presence of single nucleotide polymorphism (SNPs) rs1057141 and rs1135216 in TAP1 could influence the selection of antigenic peptides and their transport process into the rough endoplasmic reticulum for its subsequent presentation to T lymphocytes, an essential function in the defense against viral diseases and tumor processes.
Jaime Palomares‐Marin +8 more
wiley +1 more source
Prognostic role of intraparotid lymph node metastasis in primary parotid cancer: Systematic review
Abstract Background The prognostic importance of intraparotid lymph node metastasis (P+) in patients with primary parotid gland carcinoma is unclear. Methods Nineteen retrospective and noncomparative cohort studies, published between 1992 and 2020, met the inclusion criteria and included 2202 patients for this systematic review.
Orlando Guntinas‐Lichius +13 more
wiley +1 more source

