Results 1 to 10 of about 11,947 (224)

Bisphosphonate therapy in otosclerosis: A scoping review

Laryngoscope Investigative Otolaryngology, 2022
Objective Otosclerosis, a leading cause of deafness in adults, results from defective bone remodeling of the otic capsule. Bisphosphonates have been used to decrease bone remolding in many diseases, including otosclerosis.
René E. Zimmerer, Robert E. Africa, Zack K. Westenhaver, Brian J. McKinnon   +3 more
doaj   +2 more sources

Genome-wide screen of otosclerosis in population biobanks: 27 loci and shared associations with skeletal structure

Nature Communications, 2023
Otosclerosis is a common form of hearing loss, with an unclear genetic etiology. Here, the authors perform a genome-wide association study meta-analysis of otosclerosis identifying 27 genetic loci, pointing to genes involved in bone remodeling, skeletal ...
Joel T. Rämö, Tuomo Kiiskinen, Richard Seist, Kristi Krebs, Masahiro Kanai, Juha Karjalainen, Mitja Kurki, Eija Hämäläinen, Paavo Häppölä, Aki S. Havulinna, Heidi Hautakangas, FinnGen, Reedik Mägi, Priit Palta, Tõnu Esko, Andres Metspalu, Matti Pirinen, Konrad J. Karczewski, Samuli Ripatti, Lili Milani, Konstantina M. Stankovic, Antti Mäkitie, Mark J. Daly, Aarno Palotie   +23 more
doaj   +2 more sources

Imaging Studies in Otosclerosis: An Up-to-date Comprehensive Review

International Archives of Otorhinolaryngology, 2021
Introduction Otosclerosis is a primary osteodystrophy of the otic capsule, frequently responsible for acquired hearing loss in adults. Although the diagnostic value of imaging investigations in otosclerosis is debatable, they might still be employed with
Lucas Resende Lucinda Mangia, Luiz Otávio de Mattos Coelho, Bettina Carvalho, Adriana Kosma Pires de Oliveira, Rogerio Hamerschmidt   +4 more
doaj   +2 more sources

Association between systemic inflammatory markers and otosclerosis: a retrospective case–control study [PDF]

Frontiers in Neurology
ObjectiveOtosclerosis is a localized metabolic bone disease of the otic capsule with an inflammatory component. This study investigated whether otosclerosis is associated with alterations in systemic inflammatory indices, namely the Neutrophil-to ...
Hüseyin Işık, Deniz Baklaci
doaj   +2 more sources

Interventions for the Diagnosis and Management of Otosclerosis: An Umbrella Review. [PDF]

Otolaryngol Head Neck Surg
Abstract Objective Perform an umbrella review (a systematic review of systematic reviews) to identify interventions for the prevention, diagnosis, and management of otosclerosis, to inform the development of the World Health Organization (WHO) Package of Ear and Hearing Care Interventions (PEHCI). Data Sources PubMed, Scopus, and Ovid MEDLINE databases
Chau IJ, McCray LR, Nguyen SA, Labadie RF, Der C, Dillard LK.   +5 more
europepmc   +2 more sources

Assessment of Raftlin and blood count parameters in otosclerosis [PDF]

Frontiers in Neurology
ObjectiveAlthough otosclerosis is a common disease, its etiology has not yet been clearly elucidated. One of the factors recently implicated in its pathogenesis is chronic inflammation.
Duygu Erdem, Sultan Şevik Eliçora, Berrak Güven, Deniz Baklaci   +3 more
doaj   +2 more sources

Improved Bone Conduction and Hearing Outcomes After Stapes Surgery for Otosclerosis. [PDF]

World J Otorhinolaryngol Head Neck Surg
ABSTRACT Objective To evaluate the improvement in bone conduction (BC) thresholds after stapes surgery for otosclerosis, compare the outcomes of surgical techniques, and analyze the short‐ and long‐term results to inform treatment strategies. Methods We retrospectively reviewed data from 173 patients (188 ears) who underwent total stapedectomy, partial
Zhang N, Ma XB, Wang DN, Li Y, Zheng Y, Li YX, Zhao SQ.   +6 more
europepmc   +2 more sources

A Call for Screening: Hearing Loss and Chronic Otitis Media in Immigrants to Sweden. [PDF]

Laryngoscope Investig Otolaryngol
The prevalence of chronic otitis media was 2.3% and hearing impairment was found in 15.2% in this cohort of adult immigrants to Sweden attending Swedish language classes. As learning a new language is crucial to integration into society, we advocate for the inclusion of screening audiometry in the general health check‐up for immigrants.
Kraft S, Dahlin-Redfors Y, Jönsson R, Pauli N.   +3 more
europepmc   +2 more sources

Genetic basis of otosclerosis [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2020
Introduction. Otosclerosis is a disorder of the bone labyrinth and stapes resulting in conductive hearing loss. The genetic basis of otosclerosis still remains unknown. We aimed at reporting a comprehensive review of up-to-date knowledge on genetic basis
Zukić Branka, Anđelković Marina, Gašić Vladimir, Grubin Jasmina, Pavlović Sonja, Đerić Dragoslava   +5 more
doaj   +1 more source

Brazilian Society of Otology task force – Otosclerosis: evaluation and treatment

Brazilian Journal of Otorhinolaryngology, 2023
Highlights • There is no evidence that pregnancy increases the risk of developing or worsening otosclerosis.• The use of the endoscope in stapes surgery is equally as safe as the use of the microscope.• No prosthesis material is superior to another in ...
V. Silva, H. Pauna, J. Lavinsky, Guilherme Corrêa Guimarães, N. M. Abrahão, E. Massuda, M. Vianna, C. Ikino, Vanessa Mazanek Santos, J. Polanski, Mauricio Noschang Lopes Silva, A. Sampaio, Raul Vitor Rossi Zanini, Luiz Fernando Manzoni Lourençone, Mariana Moreira de Castro Denaro, Daniela Bortoloti Calil, C. Chone, A. Castilho   +17 more
semanticscholar   +1 more source