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Genetic basis of otosclerosis [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2020 Introduction. Otosclerosis is a disorder of the bone labyrinth and stapes resulting in conductive hearing loss. The genetic basis of otosclerosis still remains unknown. We aimed at reporting a comprehensive review of up-to-date knowledge on genetic basis
Zukić Branka +5 more
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Association between systemic inflammatory markers and otosclerosis: a retrospective case–control study [PDF]
Frontiers in NeurologyObjectiveOtosclerosis is a localized metabolic bone disease of the otic capsule with an inflammatory component. This study investigated whether otosclerosis is associated with alterations in systemic inflammatory indices, namely the Neutrophil-to ...
Hüseyin Işık, Deniz Baklaci
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Assessment of Raftlin and blood count parameters in otosclerosis [PDF]
Frontiers in NeurologyObjectiveAlthough otosclerosis is a common disease, its etiology has not yet been clearly elucidated. One of the factors recently implicated in its pathogenesis is chronic inflammation.
Duygu Erdem +3 more
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Does bilateral otosclerosis make pre-operative bone conduction more inaccurate?
Journal of Otology, 2021 Objectives: To assess whether bilateral otosclerosis renders pre-operative bone conduction more inaccurate by increasing the Carhart effect. Methods: Retrospective review of a database of pre and post-operative audiograms of 745 ears with otosclerosis ...
Fiona McClenaghan, Jeremy Lavy
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Insights into Imaging, 2020 Background Otosclerosis causes conductive, sensorineural and mixed hearing loss (CHL, SNHL, MHL) and tinnitus in young adults. It is best diagnosed on high-resolution CT (HRCT).
Bela Purohit +2 more
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Imaging Studies in Otosclerosis: An Up-to-date Comprehensive Review
International Archives of Otorhinolaryngology, 2021 Introduction Otosclerosis is a primary osteodystrophy of the otic capsule, frequently responsible for acquired hearing loss in adults. Although the diagnostic value of imaging investigations in otosclerosis is debatable, they might still be employed with
Lucas Resende Lucinda Mangia +4 more
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Analysis of the Genetic Characteristics of a Chinese Family With Otosclerosis
Ear, Nose & Throat Journal, 2021 Background: Otosclerosis is a focal lesion of the inner ear. The role of genetic factors in the pathogenesis of otosclerosis has received increasing attention. We analyzed the clinical manifestations, inheritance pattern, and pathogenic genes in a family
Yongli Zhang BS +5 more
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Stem Cell Research, 2022 Otosclerosis is caused by abnormal bone remodeling in the middle ear, resulting in progressive hearing loss, dizziness, balance problems, and tinnitus.
Hongmin Wu +6 more
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Cochlear Otosclerosis: An Undiagnosed Cause of Progressive Sensorineural Hearing Loss
Bengal Journal of Otolaryngology and Head Neck Surgery, 2020 Introduction Otosclerosis presents as conductive or mixed hearing loss depending upon the stage of the disease. Isolated sensorineural hearing loss though known to occur has been rarely reported.
Asish Kumar Lahiri +4 more
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Bisphosphonate therapy in otosclerosis: A scoping review
Laryngoscope Investigative Otolaryngology, 2022 Objective Otosclerosis, a leading cause of deafness in adults, results from defective bone remodeling of the otic capsule. Bisphosphonates have been used to decrease bone remolding in many diseases, including otosclerosis.
René E. Zimmerer +3 more
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