Results 21 to 30 of about 1,126 (214)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Psychology of Myth and Story; New Approach in Literary Criticism [PDF]

Matn/Pizhūhī-i Adabī, 2015
The purpose of this article, is introducing a new approach in critical studies of the text that it is useful in the field of fairy tales, folk stories, many legends and mythic stories. Psychological approach to myth is using modern theories of psychology
Maryam Hosseini, Nasrin Shakibi Momtaz   +1 more
doaj  

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Quality of Life (QoL) Assessment in the Patients Operated with Either Laparoscopic or an Open Aortobifemoral Bypass for Aortoiliac Occlusive Disease (AIOD): 2 Years Results of a Randomized Controlled Trial

Vascular Health and Risk Management, 2022
Mehdi Sahba,1,2 Anne Helene Krog,1 Erik Mulder Pettersen,3 Torbjørn Wisløff,4 Jon Otto Sundhagen,5 Syed Sajid Hussain Kazmi2,5 1Department of Vascular Surgery, Østfold Central Hospital, Kalnes, Norway; 2Institute of Clinical Medicine, Faculty of Medicine,
Sahba M, Krog AH, Pettersen EM, Wisløff T, Sundhagen JO, Kazmi SSH   +5 more
doaj  

On rank 5 projective planes

, 1984
In this paper we continue the study of projective planes which admit collineation groups of low rank (Kallaher [1] and Bachmann [2,3]). A rank 5 collineation group of a projective plane ℙ of order n≠3 is proved to be flag-transitive. As in the rank 3 and
Otto Bachmann
core   +1 more source

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Influence of Test Temperature and Test Frequency on Fatigue Life of Aluminum Alloy EN AW‐2618A

Advanced Engineering Materials, EarlyView.
The influence of test temperature and test frequency on the fatigue life of EN AW‐2618A is investigated. High‐cycle fatigue tests are performed at different test temperatures and frequencies on the 1000 h/230°C overaged state. Both test parameters reduce fatigue life due to time‐dependent damage mechanisms.
Ying Han, Julian M. Rosalie, Jan Radners, Mauro Madia, Philipp von Hartrott, Birgit Skrotzki   +5 more
wiley   +1 more source

Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration

Angewandte Chemie, EarlyView.
The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti, Hannah Dreisbach, Rémi Corlay, Clara Weber, Tamara Reiter, Wael Elaily, Bastian Daniel, Klaus Zangger, Pedro A. Sánchez‐Murcia, Mélanie Hall   +9 more
wiley   +2 more sources

The Black Swan di Darren Aronofsky. Lo specchio come indagine psicanalitica sulla pazzia

Ricerche di S/Confine, 2014
Darren Aronofsky's 'The Black Swan' is certainly one of the most emblematic and controversial movie of the recent years. Considered a masterpiece or panned brutally, echo’s a long line of films that led themselves to a psychoanalytic analysis. In attempt
Francesca Casella
doaj  

Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems

Advanced Materials, EarlyView.
DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are uptaken into fibroblast spheroids where they are actively remodeled by cellular forces depending on their mechanical properties.
Tobias Walther, Eleni Dalaka, Gotthold Fläschner, Manuel Gómez‐González, Ilia Platzman, Sadaf Pashapour, Michelle Emmert, Pere Roca‐Cusachs, Xavier Trepat, Kerstin Göpfrich   +9 more
wiley   +1 more source