Results 191 to 200 of about 168,020 (265)

Development and evaluation of a machine learning model predicting out-of-hospital cardiac arrest using environmental factors. [PDF]

NPJ Digit Med
Nakashima T, Ogata S, Kiyoshige E, Al-Hamdan MZ, Wang Y, Noguchi T, Shields TA, Al-Araji R, McNally B, Nishimura K, Neumar RW.   +10 more
europepmc   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Influence of extreme temperatures on out-of-hospital cardiac arrest cases in Hungary: a national time-series analysis. [PDF]

Resusc Plus
Nagy B, Pál-Jakab Á, Kiss B, Morvai A, Sipos B, Pápai G, Csató G, Orbán G, Boussoussou N, Merkely B, Sótonyi P, Gerencsér A, Szilágyi B, Zima E.   +13 more
europepmc   +1 more source

A real‐world data‐driven approach to optimizing enoxaparin dosing in burn patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Enoxaparin dosing in burn patients is challenging due to physiological changes affecting absorption, distribution and clearance. The objectives of this study are to develop a population pharmacokinetic (PK) model for enoxaparin in burn patients, evaluate target attainment with current equation‐based (EQ) dosing and propose an optimized dosing ...
Babajide Shenkoya, Venkata Yellepeddi, Ann Marie B. Prazak, Mathangi Gopalakrishnan   +3 more
wiley   +1 more source

Characteristics and outcomes of out-of-hospital cardiac arrest due to drowning - a nationwide registry-based study. [PDF]

Scand J Trauma Resusc Emerg Med
Hüser C, Eimer C, Wnent J, Cukoski S, Hackl MJ, Suárez V, Gräsner JT, Seewald S.   +7 more
europepmc   +1 more source

Penicillin allergy de‐labelling in the critical care unit: Simulations to design an intravenous drug provocation test that mirrors the plasma profile of an enteral challenge

British Journal of Clinical Pharmacology, EarlyView.
The majority of penicillin allergy labels are incorrect and a label of penicillin allergy is associated with worse outcomes and increased use of healthcare services. Penicillin allergy assessment and de‐labelling may be considered in critically ill patients. An oral penicillin challenge is a common component of most penicillin allergy protocols.
Cleodie Swire, Sean Keane, Reya Vinay Shah, Toqa El‐Nahhas, Iao Lei, Salma Alamin, Niall Conlon, Dagan Osborne Lonsdale   +7 more
wiley   +1 more source

Cadiology intensive care in patients with out-of-hospital cardiac arrest or cardiogenic shock. [PDF]

Resusc Plus
Garcheva V, Pfeffer TJ, Bauersachs J, Schäfer A.   +3 more
europepmc   +1 more source

Understanding the influence of transfusion and blood loss on tranexamic acid concentration in scoliosis surgery with blood loss

British Journal of Clinical Pharmacology, EarlyView.
Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá, Luisa Barreiros, Marcela A. Segundo, Eugénia Cruz, Sibylle Langenecker   +4 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

In-hospital <i>vs</i> out-of-hospital cardiac arrest in the Arab Asian countries: A contemporary review of the literature. [PDF]

World J Crit Care Med
Alkuwari H, Al-Sulaiti N, Al-Mannai W, Asim M, Al-Thani H, El-Menyar A.   +5 more
europepmc   +1 more source