Results 231 to 240 of about 168,020 (265)

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source

Predicting return of spontaneous circulation in out-of-hospital cardiac arrest resuscitated in the emergency department: a single center retrospective study. [PDF]

BMC Emerg Med
Zuo S, Wei G, Li H.
europepmc   +1 more source

Major Adverse Cardiac Events with Ondansetron: A Systematic Review

Clinical Pharmacology &Therapeutics, EarlyView.
Evidence base: 170 randomized trials, 23,421 adults, predominantly single‐dose IV ondansetron, mean follow‐up 20 days. Observed outcomes: Major adverse cardiac events were rare, no ventricular arrhythmias or torsades de pointes observed. Conclusion: Ondansetron was not associated with increased mortality or serious cardiac arrhythmias in adult ...
Michael Cristian Garcia, Bhavya Gandhi, Faisal Quadri, Mahnoor Shahab, Kassie Rong, Genevieve Ramnarine, Ishleen Sudan, Sophia Zhang, Michelle Yu, Sara Mojdehi, Lawrence Mbuagbaw, Anne M. Holbrook   +11 more
wiley   +1 more source

Cognitive Recovery After Out-of-Hospital Cardiac Arrest: Insights Into Improvement Over 6 Months and the Role of Arrest Duration. [PDF]

J Am Heart Assoc
Brouer JAE, Oestergaard LG, Eiskjær H, Bro-Jeppesen J, Qvist Kristensen L.   +4 more
europepmc   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Does out-of-hospital cardiac arrest survival differ by EMS agency type in the U.S.? Insights from the CARES registry. [PDF]

Resusc Plus
Nallamothu JL, Girotra S, Kennedy KF, Chan PS.   +3 more
europepmc   +1 more source

The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review

ESC Heart Failure, Volume 12, Issue 2, Page 733-760, April 2025.
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray, Claire McNamara, Anna V. Chatzi   +2 more
wiley   +1 more source

Patient and physician perspectives on smartwatch-based out-of-hospital cardiac arrest detection. [PDF]

Eur Heart J Digit Health
Eversdijk M, Bak MAR, Dekker LRC, van der Eerden BJW, Bruijnzeels AEC, Willems DL, Tan HL, Kop WJ, Habibović M.   +8 more
europepmc   +1 more source

Clinician perspectives on utilizing time-limited trials among patients with an out-of-hospital cardiac arrest: A qualitative study. [PDF]

Resusc Plus
Sirigiri JA, Byrd KM, Perez S, Schmitzberger F, Valley TS, Meurer W, Viglianti EM.   +6 more
europepmc   +1 more source