Results 41 to 50 of about 3,263,717 (308)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Editorial Vol15 no3

open access: yesScottish Journal of Residential Child Care, 2016
Ten years ago it would have been highly unlikely to be publishing a journal issue on a theme of love in the context of children in out of home care. It would have been considered just too left field, dangerous even, in a context of intense anxiety over ...
Mark Smith
doaj   +1 more source

Vivre une situation de placement en centre de réadaptation ou en foyer de groupe : quelles influences sur l’expérience scolaire ?

open access: yesSociétés et Jeunesses en Difficulté, 2023
Several studies have shown that there are gaps in academic achievement between youth in care and those who have never had a placement experience. Differences are also noted in relation to the number and type of placement experienced by these youths.
Élodie Marion   +2 more
doaj  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Determining the Difficulties of Parents with Children in Home Care Who Were Discharged from Intensive Care [PDF]

open access: yes
Introduction: This study was performed to determine the difficulties experienced by parents with children in home care who were discharged from intensive care.
Gülzade Uysal   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Study of care home residents’ and relatives’ expectations and experiences [PDF]

open access: yes, 2011
Care home residents who took part in a study by the Personal Social Services Research Unit (PSSRU) at the University of Kent believe their experience of living in a care home has been better than they expected when they first moved in.
Darton, Robin
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Creating a place for us: an overview of the FICE young people's conference 2004

open access: yesScottish Journal of Residential Child Care, 2004
Conferences like this allow us to get together, to share information, experiences and more importantly, it gives us an excellent opportunity to make friends.
Irene Stevens
doaj   +1 more source

Health Outcomes of Children Living in Out-of-Home Care in Metropolitan Western Australia: A Sequential Mixed-Methods Study—A Protocol Paper

open access: yesChildren, 2023
The research protocol described aims to examine and establish the health outcomes of children and young people living in Out-of-Home Care (OOHC) in Perth, Western Australia (WA) from the perspective of the care recipients and service providers.
Hope Kachila   +5 more
doaj   +1 more source

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