Results 111 to 120 of about 95,832 (259)

PDGFRα+DPP4+ Fibroblasts‐Macrophage Crosstalk Induces Orbital Fibrosis in Treatment‐Resistant Thyroid Eye Disease via the GAS6‐AXL Pathway

Advanced Science, EarlyView.
This study elucidates macrophage‐induced orbital fibrosis in TED via the GAS6‐AXL pathway, a treatment‐resistant disorder lacking non‐surgical therapies. Using a novel patient cell‐derived orthotopic animal model of orbital fibrosis for TED, we repurpose an existing fibrosis therapy, addressing the absence of stable models and offering a potential ...
Lu Cheng, Jinwei Cheng, Guiling Liang, Xiaorui Wang, Yanwen Ge, Jiapei Liu, Luwei Cai, Hui Ying, Fenfen Wang, Jing Hu, Yufan Wang, Philipp E. Scherer, Ben Zhou, Mengle Shao, Fang Zhang   +14 more
wiley   +1 more source

Out-of-hospital cardiac arrest caused by acute myocardial infarction.

, 1997
Shunji Kasaoka, Ryosuke Tsuruta, Ken Nakashima, Yoshiyuki Soejima, Daikai Sadamitsu, Akio Tateishi, Tsuyoshi Maekawa   +6 more
openalex   +2 more sources

Thrombolysis using recombinant tissue-type plasminogen activator during cardiopulmonary resuscitation in patients with out-of-hospital cardiac arrest [PDF]

, 2002
Bernd W. Böttiger, Stephan A. Padosch
openalex   +1 more source

Decreased RYR2 Cluster Size and Abnormal SR Ca2+ Release Contribute to Arrhythmogenesis in TMEM43‐Related ARVC

Advanced Science, EarlyView.
The TMEM43 ‐ P386S mutation causes arrhythmogenic right ventricular cardiomyopathy (ARVC) by mislocalizing itself from nuclear envelope (NE) to cytoplasm, disrupting lamin B2 (a novel TMEM43 interactor) localization, NE integrity and chromatin accessibility, causing hyper ‐ phosphorylation and reduced expression/clustering of ryanodine receptor type 2 (
Jiaxi Shen, Xiaochen Wang, Hangping Fan, Yaxun Sun, Tingyu Gong, Hangyuan Qiu, Jue Wang, Ziwei Pan, Yanna Dang, Hongkun Wang, Danni Zhou, Tianyi Zhu, Hao Wang, Xianzhen Chen, Lizhen Xu, Jun Su, Fan Yang, Yiquan Tang, Xuguang Li, Bing Yang, Lenan Zhuang, Wei Wang, Chenyang Jiang, Ping Liang   +23 more
wiley   +1 more source

Memory Impairment in Out-of-Hospital Cardiac Arrest Survivors Is Associated With Global Reduction in Brain Volume, Not Focal Hippocampal Injury

, 2000
Neil R. Grubb, Keith A.A. Fox, Karen Bulmer Smith, Jonathan Best, Annette Blane, Klaus P. Ebmeier, Michael F. Glabus, Ronan E. O’Carroll   +7 more
openalex   +1 more source

Bimetal‐Phenolic Framework to Combat Bacterial Infections via Synergistic Biofilm Dispersal, Bacterial Killing and Immune Modulation

Advanced Science, EarlyView.
A bimetal‐phenolic framework (Que‐Fe‐CeMPF) is developed by direct self‐assembly through the coordination of Fe3+ and Ce4+ with quercetin. Que‐Fe‐CeMPF exhibits multimodal activity, including cleaving matrix eDNA within biofilm, generating hydroxyl radicals via catalytic H2O2 to kill bacteria, and alleviating inflammation by stimulating macrophage ...
Yaran Wang, Fan Wu, Lei Hua, Chang Gao, Siran Wang, Yong Liu, Yijin Ren, Linqi Shi, Henny C. van der Mei, Yuanfeng Li   +9 more
wiley   +1 more source

Incidence and Characteristics of Out-of-Hospital Cardiac Arrest in 5 International Regions. A Comparison of Prospective Studies.

, 2000
Yasuyuki Hayashi, Atsushi Hiraide, Hiroshi Morita, Hirotsugu Akashi, Isao Nishihara, Hitoshi Yamamura   +5 more
openalex   +2 more sources

A short delay from out of hospital cardiac arrest to call for ambulance increases survival [PDF]

, 2003
Johan Herlitz
openalex   +1 more source

Antioxidant Carbon Dot of Selenomethionine Alleviates Oxidative Stress in Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A selenomethionine‐derived carbon dot (Se‐Met‐CD) serves as a potent nano‐antioxidant, efficiently scavenging reactive oxygen species, protecting nucleus pulposus cells from oxidative damage, restoring extracellular matrix homeostasis, and significantly mitigating intervertebral disc degeneration in vivo, which demonstrates great promise as a nanozyme ...
Qingzheng Zhang, Zongtai Liu, Yirong Sun, Changfeng Fu, Jianxun Ding   +4 more
wiley   +1 more source

Characteristics and outcome among patients having out of hospital cardiac arrest at home compared with elsewhere [PDF]

, 2003

openalex   +1 more source