Results 141 to 150 of about 179,681 (354)

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

Out of hospital cardiac arrest in Western Sydney - an analysis of outcomes and estimation of future eCPR eligibility [PDF]

, 2021
P. Chandru, Tatum Priyambada Mitra, Nitesh D Dhanekula, Mark Dennis, Adam Eslick, Natalie Kruit, Andrew Coggins   +6 more
openalex   +1 more source

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS‐STING Activation for Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang, Yiwei Tian, Feiyu Zhao, Yue Han, Kongshuo Ma, Linna Hai, Kaiqing Yun, Yueyang Zhao, Siqi Zhang, Ziyi Zhang, Yuxuan Peng, Kuan Hu, Jing Zhong, Bai Xiang, Zhaohui Wang   +14 more
wiley   +1 more source

Mechanical circulatory support for refractory out-of-hospital cardiac arrest: a nationwide multicentre study [PDF]

, 2021
S R Moerk, Carsten Stengaard, Louise Linde, Jacob Eifer Møller, Jo Bønding Andreasen, Helle Laugesen, Sisse Anette Thomassen, Phillip Freeman, Steffen Christensen, Mariann Tang, Emilie Gregers, Jesper Kjærgaard, Christian Hassager, Hans Eiskjær, C J Terkelsen   +14 more
openalex   +1 more source

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Post resuscitation electrocardiogram for coronary angiography indication after out-of-hospital cardiac arrest

, 2020
Florence Leclercq, Clément Lonjon, Grégory Marin, Mariama Akodad, François Roubille, Jean‐Christophe Macia, Luc Cornillet, Richard Gervasoni, Laurent Schmutz, Bertrand Ledermann, P Colson, Guillaume Cayla, Benoît Lattuca   +12 more
openalex   +2 more sources

Treatment for Out-of-Hospital Cardiac Arrest [PDF]

, 2014
Graham Nichol, Jo Ann Elrod, Lance B. Becker   +2 more
openalex   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

Advanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu, Leyan Xuan, Yingying Hou, Ting Xie, Jieting Li, Junjie Cai, Siyu Zhang, Yingling Miao, Ning Hou, Gen He, Maobin Xie, Xiyong Yu, Mingen Xu, Guosheng Tang   +13 more
wiley   +1 more source

Ventilation during out-of-hospital cardiac arrest [PDF]

Resuscitation, 2020
Sion, Jo, Jae Baek, Lee
openaire   +2 more sources

Timing of Percutaneous Coronary Intervention and Therapeutic Hypothermia in Patients With ST-Elevation Myocardial Infarction and Out-of-hospital Cardiac Arrest [PDF]

, 2017
Craig Basman, Michael C. Kim, Neil L. Coplan   +2 more
openalex   +1 more source