Results 201 to 210 of about 179,681 (354)

Co‐Opting MBNL‐Dependent Alternative Splicing Cassette Exons to Control Gene Therapy in Myotonic Dystrophy

Annals of Neurology, EarlyView.
Objective Myotonic dystrophy type 1 (DM1) is a highly variable, multisystemic genetic disorder caused by a CTG repeat expansion in the 3′ untranslated region of DMPK. Toxicity is exerted by repeat‐containing DMPK transcripts that sequester muscleblind‐like (MBNL) proteins and lead to deleterious yet predictable changes in alternative splicing.
Samuel T. Carrell, Ellie M. Carrell, Ryan Giovenco, Beverly L. Davidson   +3 more
wiley   +1 more source

Benefits of targeted deployment of physician-led interprofessional pre-hospital teams on the care of critically ill and injured patients: a systematic review and meta-analysis

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Adam J. Boulton, Terry Brown, Joyce Yeung   +2 more
doaj   +1 more source

Amiodarone for out-of-hospital cardiac arrest [PDF]

CJEM, 2000
M J, Bullard, J, Vipond
openaire   +2 more sources

Real-world cost-effectiveness of targeted temperature management in out-of-hospital cardiac arrest survivors: results from an academic medical center [PDF]

Wachira Wongtanasarasin, Daniel K. Nishijima, Wanrudee Isaranuwatchai, Jeffrey S. Hoch   +3 more
openalex   +1 more source

Timing of Peri‐Ictal MRI Abnormalities in Status Epilepticus – One Size Does Not Fit All

Annals of Neurology, EarlyView.
Objective We aimed to investigate timing of occurrence of peri‐ictal MRI abnormalities – a potential risk biomarker of status epilepticus‐related cerebral injury (t2). Methods This prospective study enrolled adult patients with status epilepticus and acute magnetic resonance imaging (MRI); patients with peri‐ictal MRI abnormalities underwent follow‐up ...
Pilar Bosque Varela, Lukas Machegger, Tanja Prüwasser, Wanda Lauth, Jürgen Steinbacher, Andreas Oellerer, Georg Zimmermann, Johannes Pfaff, Mark McCoy, Bernardo Crespo Pimentel, Markus Leitinger, Eugen Trinka, Giorgi Kuchukhidze   +12 more
wiley   +1 more source

Prehospital thrombolysis with tenecteplase in out-of-hospital cardiac arrest: a retrospective cohort study. [PDF]

Scand J Trauma Resusc Emerg Med
Cowley A, Cody D, Jaquet E, Corb S, Nelson M.   +4 more
europepmc   +1 more source

Clinical Survey and Predictors of Outcomes of Pediatric Out-of-Hospital Cardiac Arrest Admitted to the Emergency Department [PDF]

, 2019
Jung Lee, Wen‐Chieh Yang, En‐Pei Lee, Jing‐Long Huang, Hsiang-Ju Hsiao, Mao-Jen Lin, Han‐Ping Wu   +6 more
openalex   +1 more source

Temporal trends of suicide-related non-traumatic out-of-hospital cardiac arrest characteristics and outcomes with the COVID-19 pandemic

, 2022
Justin Yap, Frank Scheuermeyer, Sean van Diepen, David Barbic, Ron Straight, Nechelle Wall, Michael Asamoah-Boaheng, Jim Christenson, Brian Grunau   +8 more
openalex   +1 more source

A Novel Transcriptional Slippage Mechanism Rescues Dystrophin Expression from a DMD Frameshift Variant

Annals of Neurology, EarlyView.
Pathogenic DMD variants usually follow the reading‐frame rule: out‐of‐frame changes cause Duchenne muscular dystrophy, whereas in‐frame ones produce Becker muscular dystrophy (BMD). We report a 23‐year‐old man with BMD‐like weakness, calf hypertrophy, elevated creatine kinase, and dilated cardiomyopathy.
Hiroya Naruse, Jun Mitsui, Akatsuki Kubota, So Okubo, Shuichiro Mitsuchi, Kensho Sumi, Shuichi Tanifuji, Shogo Komaki, Asuka Kitamura, Meiko Maeda, Daiki Yashita, Atsushi Sudo, Takashi Matsukawa, Masashi Hamada, Wataru Satake, Shoji Tsuji, Tatsushi Toda   +16 more
wiley   +1 more source

Pre-hospital management of traumatic cardiac arrest 2024 position statement: Faculty of Prehospital Care, Royal College of Surgeons of Edinburgh

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Celestine Weegenaar, Zane Perkins, David Lockey   +2 more
doaj   +1 more source