Results 201 to 210 of about 95,832 (259)

Outcomes of Fluoroscopy‐Based Asymmetric Underexpansion With the Self‐Expanding ACURATE Neo and Neo2 Valve

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Asymmetric underexpansion of transcatheter heart valves (THVs), as observed on fluoroscopy, may influence prosthesis function or long‐term durability of transcatheter aortic valve implantation (TAVI). Aims This study aimed to evaluate the effect of stent frame asymmetry on hemodynamic performance and clinical outcomes in ACURATE neo
Daisuke Sato, Noriaki Moriyama, Hirokazu Miyashita, Yoichi Sugiyama, Tommi Vähäsilta, Teemu Laakso, Sebastian Dahlbacka, Tiina Vainikka, Juho Viikilä, Mika Laine, Mikko Jalanko   +10 more
wiley   +1 more source

Are Women at Higher Risk for Isolated Surgical Aortic Valve Replacement? Results From 178,000 STS Adult Cardiac Surgery Database Patients

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Female sex is a well‐established risk factor for morbidity and mortality in cardiac surgery. Aims This study aimed to assess the characteristics and contemporary outcomes of surgical aortic valve replacement (SAVR) in women compared to men. Methods All patients who underwent isolated SAVR from 2014 through 2022 were identified using
Takuya Ogami, Irsa Hasan, Julie A. Phillippi, Derek Serna‐Gallegos, Carlos E. Diaz‐Castrillon, Ibrahim Sultan   +5 more
wiley   +1 more source

Comparison of in‐Hospital Complication Rates After Transcatheter Aortic Valve Replacement in Patients With Bicuspid Versus Tricuspid Aortic Valves: A Retrospective Cohort Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter aortic valve replacement (TAVR) has become a popular alternative to surgical aortic valve replacement (SAVR) for patients with valvular heart disease (VHD), particularly for those with aortic anomalies. Aims The study aimed to compare the risks of post‐TAVR complications between patients with bicuspid and tricuspid ...
Tingxi Zhu, Jiawei Luo, Xuan Huang, Lulu Liu, Kehan Li, Wei He, Xiaobo Zhou, Yingqiang Guo, Xiaoyan Yang   +8 more
wiley   +1 more source

Therapeutic hypothermia in comatose patients after out‐of‐hospital cardiac arrest*

, 2007
Alastair Hay, David Swann, Karen Bell, Timothy Walsh, Brian Cook   +4 more
openalex   +1 more source

Applying DanGer Shock Eligibility Criteria to a Real‐World Cohort of Cardiogenic Shock Patients

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The DanGer Shock trial investigated the effects of adding a microaxial flow pump to guideline‐recommended therapy in patients with ST‐elevation myocardial infarction (STEMI)‐related cardiogenic shock (CS), finding a lower all‐cause mortality at 180 days in the intervention group.
Raffaela Miriam Planka, Lukas Herold, Theresa Glantschnig, Gudrun Sommer, Jonathan Pavek, Stefan Hatzl, Nicolas Verheyen, Christoph Strohhofer, Johannes Gollmer, Ewald Kolesnik, Martin Benedikt, Markus Wallner, Andreas Zirlik, Gabor Toth‐Gayor, Dirk von Lewinski   +14 more
wiley   +1 more source

The Prognostic Value of Troponin in Acute Pulmonary Embolism: A Systematic Review and Meta‐Analysis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Acute pulmonary embolism (PE) is a major cause of cardiovascular morbidity and mortality. Troponin elevation is increasingly used for risk stratification, but its prognostic utility remains variably reported across studies. To evaluate the prognostic value of troponin elevation in patients with acute PE, concerning short‐term mortality and ...
Ahmed T. Elmewafy, James Waller, Priyanth Alaguraja, Kishan Desor, Ibrahim Antoun   +4 more
wiley   +1 more source

Titin Is Present in the Elastic Tethers That Connect Separating Anaphase Chromosomes in Crane‐Fly Spermatocytes

Cytoskeleton, EarlyView.
ABSTRACT Elastic tethers connect telomeres of separating chromosomes in anaphase of animal cells. Immunofluorescence staining of titin in crane‐fly spermatocytes, using 4 different antibodies, shows that the giant elastic protein titin seems to be a component of mitotic tethers: titin “strands” extend between separating chromosomes, connecting their ...
Demetra Economopoulos, Maral Janan, Martina Krüger, Aavo‐Valdur Mikelsaar, Arthur Forer, Rose Sheykhani   +5 more
wiley   +1 more source

Pharmacokinetics, Tolerability, and Biomarker Profile of the Neurokinin 3 Receptor Antagonist Fezolinetant in Healthy Japanese Individuals: A 2‐Part, Randomized, Phase 1 Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This 2‐part, randomized, placebo‐controlled, double‐blind, Phase 1 study analyzed the pharmacokinetics, safety, and biomarker profile of fezolinetant in healthy Japanese individuals. Part 1: male participants received single doses of placebo or fezolinetant 15 or 60 mg.
Akira Koibuchi, Megumi Iwai, Kanji Komatsu, Kentaro Kuroishi, Mai Shibata, Masako Saito, Jace Nielsen, Jiayin Huang, Shunji Matsuki   +8 more
wiley   +1 more source

Results of the ACCOuNT Trial: A Multi‐Institutional Prospective Pharmacogenomics Implementation Trial for African American Inpatients

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang, Kevin J. O'Leary, Edith A. Nutescu, Matthew Jack, Thomas Chen, Gregory W. Ruhnke, James C. Lee, David George, Larry K. House, Randall Knoebel, Luke V. Rasmussen, Seth Hartman, Anish Choksi, Kiang‐Teck J. Yeo, Minoli A. Perera, Mark J. Ratain, David O. Meltzer, Peter H. O'Donnell   +17 more
wiley   +1 more source

Clinical Trials With Pragmatic Elements: A Review of Use Cases and Real‐World Data Utilization

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical trials with pragmatic elements can capture diverse patient populations, enable efficient follow‐up, and reflect routine clinical practices; yet there is limited understanding of their design features, characteristics, and use of real‐world data (RWD). Based on a targeted search of PubMed/EMBASE (Jan‐2016 to Jul‐2024), a review was conducted to
Le Su, Lei Chen, Seema Betigeri, Nancy Dreyer, Helga Gardarsdottir, Rachele Hendricks‐Sturrup, Mehmet Burcu   +6 more
wiley   +1 more source