Results 41 to 50 of about 168,041 (302)

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Improving out‐of‐hospital notification in traumatic cardiac arrests with novel usage of smartphone application

Journal of the American College of Emergency Physicians Open, 2020
Introduction Timely out‐of‐hospital notifications in patients with traumatic cardiac arrest are associated improvements in mortality. Details surrounding these events are often limited, and decisions to perform advanced resuscitative procedures must be ...
Geoffrey S. Kelly, Drew Clare
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Out-of-hospital cardiac arrest

, 2022
Out-of-hospital cardiac arrest (OHCA) is a major public health problem that accounts for 50% of all deaths from cardiovascular causes in Western societies. OHCA is usually caused by cardiac arrhythmias (ventricular tachycardia [VT], ventricular fibrillation [VF]).
Eroglu, T. E., Blom, M.T.
  +6 more sources

The association between hemoglobin concentration and neurologic outcome after cardiac arrest. [PDF]

, 2016
PURPOSE: The purpose of the study is to determine the association between hemoglobin concentration (Hgb) and neurologic outcome in postarrest patients. METHODS: We conducted a retrospective cohort study using the Penn Alliance for Therapeutic Hypothermia
Dodampahala, Kalani, Gaieski, David F., Goyal, Munish, Grossestreuer, Anne V., Johnson, Nicholas J., Perman, Sarah M., Rosselot, Babette   +6 more
core   +1 more source

National initiatives to improve outcomes from out-of-hospital cardiac arrest in England [PDF]

, 2015
NHS England report that the ambulance services attempt to resuscitate approximately 28 000 people from out-of-hospital cardiac arrest each year (approximately 1 per 2000 inhabitants per year).1 The rate of initial success (return of spontaneous ...
de Belder, Mark, Gray, Huon, Lockey, Andrew S., Moore, Fionna, Perkins, Gavin D., Weissberg, Peter   +5 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Variation of current protocols for managing out-of-hospital cardiac arrest in prehospital settings among Asian countries

Journal of the Formosan Medical Association, 2016
Protocols for managing patients with out-of-hospital cardiac arrest (OHCA) may vary due to legal, cultural, or socioeconomic concerns. We sought to assess international variation in policies and protocols related to OHCA.
Chih-Hao Lin, Yih Yng Ng, Wen-Chu Chiang, Sarah Abdul Karim, Sang Do Shin, Hideharu Tanaka, Tatsuya Nishiuchi, Kentaro Kajino, Nalinas Khunkhlai, Matthew Huei-Ming Ma, Marcus Eng Hock Ong   +10 more
doaj   +1 more source

Assessing Variability in End-of-Life Intensity of Care After Out-of-Hospital Cardiac Arrest [PDF]

, 2017
Out of hospital cardiac arrest (OHCA) affects over 300,000 Americans per year.1 Many factors affect the outcomes and overall OHCA survival in a community; some of these include an individual’s characteristics such as age, co-morbid conditions ...
Carr, MD, MA, MS, Brendan G., Ferd, MD Candidate, Polina, Karp, MUSA, David, Zebrowski, PhD Candidate, Alexis   +3 more
core   +1 more source

Effect of Inhaled Xenon on Cerebral White Matter Damage in Comatose Survivors of Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial [PDF]

, 2016
IMPORTANCE: Evidence from preclinical models indicates that xenon gas can prevent the development of cerebral damage after acute global hypoxic-ischemic brain injury but, thus far, these putative neuroprotective properties have not been reported in human
Airaksinen, J, Arola, O, Bäcklund, M, Grönlund, J, Harjola, VP, Hynninen, M, Inkinen, O, Korpi, K, Laitio, R, Laitio, T, Martola, J, Maze, M, Niiranen, J, Nukarinen, E, Olkkola, KT, Parkkola, R, Pietilä, M, Roine, RO, Saraste, A, Saunavaara, J, Scheinin, H, Silvasti, P, Silvennoinen, H, Tiainen, M, Vahlberg, T, Valanne, L, Varpula, M, Virtanen, S, Wennervirta, J, Ylikoski, E   +29 more
core   +2 more sources