Results 141 to 150 of about 1,106,922 (310)

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Technology enhanced learning in 21st century mass higher education. Aspects of design, practice and strategy for a necessary step change [PDF]

, 2009
Modern day mass higher education presents challenges for both learners and teachers. Whilst digital resources, Web 2.0 technologies and online connectivity can add significantly to the learning opportunities of 21st century students, many cross programme
Dickinson, John
core  

PolyGraph – Flexible, Biocompatible & Electrically Optimized Graphene‐Polymer Composites for Next‐Generation Neural Interfaces

Advanced Healthcare Materials, EarlyView.
PolyGraph, a flexible graphene‐polycaprolactone nanocomposite, unites conductivity, biocompatibility, and processability for next‐generation neural interfaces. Fabricated into microneedle arrays with ultra‐flexible backings, PolyGraph enables bidirectional neuronal recording and stimulation in brain tissue, advancing brain‐computer interface (BCI) and ...
Jack Maughan, Ian Woods, Cian O'Connor, Pablo Quintana‐Sarti, Eoin Caffrey, Jose M. Munuera, Tian Carey, Adrian Dervan, Alejandro López Valdés, Omar Mamad, Maeve A. Caldwell, Fergal J. O'Brien, Jonathan N. Coleman   +12 more
wiley   +1 more source

Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents

Advanced Healthcare Materials, EarlyView.
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn, Yongbin Ko, Juan S. Barajas‐Gamboa, Juan P. Pantoja, Oraib Al‐Ketan, Mohamed Ali, Sungyun Sohn, Heba Tageldeen Naser, Abdel‐Hameed Dabbour, Batoul Khlaifat, Ahmed AlZubaidi, Carlos Abril Vega, John Rodriguez, Matthew Kroh, Khalil B. Ramadi   +14 more
wiley   +1 more source

Preservice Mathematics Teachers’ Opinions on the Out of School Learning Environments

Eğitimdeki yeniliklerden biri öğretimi okul dışı öğrenme ortamlarına taşımak olabilir. Sınıf kapısından çıktığımız anda öğretimin gerçekleştirildiği her mekân okul dışı öğrenme ortamı olarak tanımlanabilmektedir. Bu çalışmada ilköğretim matematik öğretmen adaylarının okul dışı öğrenme ortamlarıyla ilgili görüşlerini ortaya koymak amaçlanmıştır ...
Aydoğdu, Mustafa Zeki, Aydoğdu, Ayşe Simge   +1 more
openaire   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Having fun and raising awareness: Italian students monitor airborne microplastic in school environments

Current Research in Environmental Sustainability
Although microplastics (MP, < 5 mm) are pervasive in the atmosphere and soil, with most of their sources concentrated in urban areas, public perception on MP as an environmental issue is still confined mostly to seas and oceans.
E. Bergami, V. Ferrari, M. Scaramelli, S. Righi, D. Prevedelli   +4 more
doaj   +1 more source

Evaluation of activity-based mathematics teaching to students with learning disabilities in out-of-school learning environments

Journal of Pedagogical Sociology and Psychology, 2023
Tunahan Filiz, Gönül Güneş
openaire   +2 more sources

Optimal learning spaces: design implications for primary schools [PDF]

, 2009
Review guide of the design evidence for primary ...
Barrett, PS, Zhang, Y
core