Results 41 to 50 of about 879,725 (299)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Investigating the Factors Affecting Out-of-Pocket in Hospitals Affiliated to Mazandaran University of Medical Sciences

Rāhburdhā-yi Mudīriyyat dar Niẓām-i Salāmat, 2019
Background: Out-of-pocket is one of the most important payment methods in Iran's health system, which has negative impacts on equity and pushes the vulnerable groups into poverty.
Niloofar Alikhani, Mahya Abbasi, Alireza Fathi   +2 more
doaj  

IJCM_202A: Catastrophic health expenditure (CHE) due to diabetes mellitus among urban slum population of Agra city- An Observational study

Indian Journal of Community Medicine
Background: People with diabetes need extensive self-management support, medications, regular screening for and treatment of possible complications and comorbidities, all of which can increase out-of-pocket (OOP) costs in patients and their families ...
Lingareddy Prathyusha, Renu Agrawal, Geetu Singh, Sarvesh Kumar   +3 more
doaj   +1 more source

Superconductivity from repulsion in LiFeAs: novel s-wave symmetry and potential time-reversal symmetry breaking

, 2014
We analyze the structure of the pairing interaction and superconducting gap in LiFeAs by decomposing the pairing interaction for various kz cuts into s- and d-wave components and by studying the leading superconducting instabilities.
Ahn, F., Borisenko, S. V., Büchner, B., Chubukov, A. V., Eremin, I., Knolle, J., Zabolotnyy, V. B.   +6 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Households of tuberculosis (TB) patients face high TB-related costs in Somalia

BMC Global and Public Health
Background The out-of-pocket spending and costs incurred by households affected by tuberculosis (TB) while accessing TB services in Somalia remain unclear.
Joseph Kuye, Ireneaus Sebit Sindani, Mukhtar Abdi Shube, Mohamed Jafar Salah, Abukar Ali Hilowle, Vianney Rusagara, Faith Ngima, Michael Lei Abaasiku, Stephen Balogun, Barinaadaa Afirima, Emmanuel Olashore, Abiodun Hassan   +11 more
doaj   +1 more source

IJCM_236A: Out-of-pocket expenditure on healthcare among geriatric population in central Kerala

Indian Journal of Community Medicine
Background: India is facing dual challenges caused by a rapid increase in burden of non-communicable diseases, marking epidemiological transition and an unprecedented expansion of geriatric population.
Merin Mariam Roy, Jose Vincent
doaj   +1 more source

Yarning up about out‐of‐pocket healthcare expenditure in burns with Aboriginal families

Australian and New Zealand Journal of Public Health, 2021
Objective: This study sought to understand the impact of out‐of‐pocket healthcare expenditure (OOPHE) on Aboriginal families of children with acute burns injury.
Courtney Ryder, Tamara Mackean, Kate Hunter, Julieann Coombes, Andrew J.A. Holland, Rebecca Ivers   +5 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Determination of Direct and Indirect Costs Incurred by Tuberculosis Patients During Diagnosis and Treatment in Urban Areas of South Gujarat: A Mixed Method Approach

Indian Journal of Community Medicine
Though many initiatives and monetary benefits are incorporated under RNTCP/NTEP, many patients might incur some out-of-pocket expenditure (OOP) related to diagnosis, treatment, and hospitalization. Such costs lead to further poverty and default.
Rutu Buch, Rahul Damor, J. K. Kosambiya
doaj   +1 more source