Results 71 to 80 of about 167,946,764 (290)
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
The Risk of Out-of-Pocket Health Care Expenditure at End of Life [PDF]
There is conflicting evidence on the importance of out-of-pocket medical expenditures as a risk to financial security, particularly at older ages. We revisit this question, focusing on health care spending near the end of life using data from the Health ...
Samuel Marshall +2 more
core
Out-of-pocket payments in hospital bills: a challenge to management
, 2018 Objetive: To analyse out-of-pocket payments (OOP) by health insurance company in hospital bills. Method: Cross-sectional study with quantitative approach.
July Anne Rossi Michelin Rodrigues (5839508) +3 more
core +1 more source
بیمارستان, 2013 Background: The different effective factors on out of pocket payment (OOP)have been introduced as follows: low salary of the employee's, low governmental tariff, chronic disease, gifts to personnel, physician and other cadre's requests, fear of bad or no
RGH vahidi, M Saadati
doaj
Out-of-pocket (OOP) costs incurred by breast cancer patients in Poland
Oncology in Clinical PracticeINTRODUCTION: Breast cancer is the most frequently diagnosed malignant tumor in women worldwide, the treatment of which, despite being financed by public systems, generates significant costs borne directly by patients. Aim: The study aimed to analyze out-
Mikołaj Bartoszkiewicz +5 more
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
The Effect of the Risk of Out-of-Pocket Spending for Health Care on Economic Preparation for Retirement [PDF]
After retirement, the primary sources of uncertainty with respect to an individual’s economic status are longevity, investment outcomes and out-of-pocket spending on health care.
Susann Rohwedder, Michael D. Hurd
core
Out-of-Pocket Expenditures for Most Recent Chronic Disease Care Among Syrian Refugees in Jordana.
, 2016 Out-of-Pocket Expenditures for Most Recent Chronic Disease Care Among Syrian Refugees in Jordana.
Emily Lyles (3174990) +5 more
core +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Out-of-pocket health expenditures in Australia: A semi-parametric analysis, CHERE Working Paper 2006/15 [PDF]
Out-of-pocket health expenditures in Australia are high in international comparisons and have been growing at a faster rate than most other health costs in recent years.
Elizabeth Savage +2 more
core