Results 241 to 250 of about 27,718 (292)

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall   +3 more
wiley   +1 more source

WONOEP XVII appraisal: The role of the extracellular matrix in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract The extracellular matrix (ECM) is composed of proteoglycans and glycoproteins that regulate the external environment surrounding neurons, glia, and the vascular system. The ECM is vital for maintaining the structure and function of the brain and also acts as a reservoir for various signaling molecules and neurotransmitters, modulating synaptic
Eleonora Lugara   +7 more
wiley   +1 more source

Out-of-pocket expenditure among patients with diabetic foot ulcer in a tertiary care hospital of south India: A cross-sectional study. [PDF]

open access: yesInt Wound J
Seshadri H   +9 more
europepmc   +1 more source

A price check on the ketogenic diet for adults with epilepsy in Australia

open access: yesEpilepsia Open, EarlyView.
Abstract Objective The ketogenic diet is an established and effective treatment for drug‐resistant epilepsy and is an emerging therapy for other conditions. Affordability of therapeutic ketogenic diets for epilepsy has not been well studied. This study aimed to compare weekly cost of ketogenic diets with national dietary guidelines and a typical ...
Lillian King   +6 more
wiley   +1 more source

Blade Count and Rotational Speed Sensitivity of Vertical‐Axis Turbines Under Guided Vehicle‐Generated Transient Wakes

open access: yesEnergy Science &Engineering, EarlyView.
Passing vehicles generate short‐duration wakes that can be redirected toward a vertical‐axis turbine. The interaction between wake structure, blade count, and rotational speed governs transient torque production. Low‐solidity configurations combined with tuned rotational speed enhance energy extraction under vehicle‐induced gusts.
Aydin Ulus, Stefan Ilie Moldovan
wiley   +1 more source

A Review on Carbon‐Based and Metal‐Based Anode Materials of Microbial Fuel Cells

open access: yesEnergy Science &Engineering, EarlyView.
Reviews a wide range of anode materials used in microbial fuel cells (MFCs) and evaluates their performance and suitability for scalable energy recovery from wastewater. Defines the essential characteristics of an ideal anode, including high surface area, excellent electrical conductivity, strong biocompatibility, and cost‐effectiveness, while ...
Md. Hamidur Rahman   +1 more
wiley   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

open access: yesEnvironmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz   +9 more
wiley   +1 more source

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