Results 111 to 120 of about 10,065,466 (362)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Youth Physical Activity Patterns During School and Out-of-School Time
Children, 2018 This study describes age, sex, and season patterns in children’s physical activity behaviors during discrete time periods, both in school and at home.
P. Saint-Maurice +3 more
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Book Review—Social and Emotional Learning in Out-of-School-Time: Foundations and Futures
Journal of Youth Development, 2019 Social and Emotional Learning in Out-of-School Time: Foundations and Futures (Delaney & Moroney, 2018) offers a rich volume of experiences and voices of leadership in social and emotional learning (SEL) in out-of-school time (OST) settings.
T. N. Gannon
semanticscholar +1 more source
Act Out, Get Out? Considering the Impact of School Discipline Practices in Massachusetts [PDF]
, 2010 Recently, testimony from three public hearings in Massachusetts suggested that excessive disciplinary action for non-violent offenses, such as tardiness and truancy, exacerbates the dropout crisis.
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STUDY SUCCES AS A FUNCTION OF OUT-OF-SCHOOL SPORTS ACTIVITIES
Studia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae, 2019 Study success is usually closely related to the popularity of certain subjects and the sport activities. The purpose of our study is to highlight the connection between the participation of students in out-of-school sports activities and their success in
Marianna MORAVECZ, Ágoston NAGY
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Out-of-school time matters: activity involvement and positive development among Coos County youth [PDF]
, 2010 This brief looks at the connections between how youth spend their free time and positive or negative attitudes about themselves and their future plans.
Sharp, Erin H.
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Falling Out of the Lead: Following High Achievers Through High School and Beyond [PDF]
, 2014 A previous Education Trust report, "Breaking the Glass Ceiling of Achievement for Low-Income Students and Students of Color", described inequities at the high end of the achievement spectrum and found that gaps at the advanced level on the 12th-grade ...
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