Results 131 to 140 of about 10,065,466 (362)

The Effectiveness of an Online Credit Recovery Program on Improving the Graduation Rates of Students at Risk of School Failure [PDF]

, 2018
Students are dropping out of high school at alarming rates. Reports suggest that between 6,300 and 7,000 high school students drop out daily (Dessoff, 2009; Stanley & Plucker, 2008), and more than 1.3 million students drop out each year (Long-Coleman ...
Ballenger, Julia, Eddy, Carrie
core   +1 more source

Out of school children and child protection: Understanding and improving the quality of data on out of school children

Child Protection and Practice
This practice perspective article focuses on an at-risk group often in need of further support and protection, out of school children. To evaluate whether child protection services are meeting the needs of our out of school children, reliable, accurate ...
William C. Smith
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Out of School and Out of Work

, 2014
The proportion of youth that is not in work or in school or ninis1 in Latin America and the Caribbean (LAC) remains high. The latest estimates show that about 19 per cent of 15-24 years olds in the region, were in this status in 2010 (de Hoyos, Rogers and Popova (2013).
Behrman, Jere R., de Hoyos, Rafael, Székely, Miguel   +2 more
openaire   +1 more source

KS3 and KS4 learners' use of Web 2.0 technologies in and out of school - summary [PDF]

, 2008
This is a summary of the second report from research commissioned by Becta into Web 2.0 technologies for learning at Key Stages 3 and 4. This report describes findings from data collected using a guided survey of 2,611 Year 8 and Year 10 pupils and 60 ...
Clark, Wilma, Graber, Rebecca, Logan, Kit, Luckin, Rose, Mee, Adrian, Oliver, Martin   +5 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Out of School and Out of Work

, 2016
Using all the household survey data available in Latin America during the period 1992 to 2013, this paper estimates that in 2015, 20 million youth ages 15 to 24 years in the region were out of school and not working (making them ninis, for "ni estudian ni trabajan"). The share of out-of–school,
de Hoyos, Rafael, Popova, Anna, Rogers, Halsey   +2 more
openaire   +1 more source

Gateway to College: Lessons from Implementing a Rigorous Academic Program for At-Risk Young People [PDF]

, 2015
Despite efforts to improve the high school graduation rate in the United States, an estimated 7,200 students drop out of high school every day -- a staggering 1.3 million every year.
Brian Bayes, Jacklyn Altuna Willard, John Martinez   +2 more
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source