How Educators Can Eradicate Disparities in School Discipline: A Briefing Paper on School-Based Interventions [PDF]
, 2014 The number of students issued suspensions in U.S. schools continues to be extremely high, resulting in thousands of students missing school every day. Simultaneously,disparities in school suspension continue to worsen, indicating that students in some ...
Anne Gregory, James Bell, Mica Pollock
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Getting Started With Market Research for Out-of-School Time Planning: A Resource Guide for Communities [PDF]
, 2007 Shows community leaders, policymakers, and out-of-school-time practitioners how to use market research to make more informed programming and planning ...
Elizabeth Denny +4 more
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Out of School and Off Track: The Overuse of Suspensions in American Middle and High Schools [PDF]
, 2013 Analyzing data from over 26,000 U.S. middle and high schools, the report reveals profound disparities in suspension rates when disaggregating data by race/ethnicity, gender, and disability status.
Daniel J. Losen, Tia Martinez
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Too much free time: Coos County Youth who are least involved in out-of-school activities are most likely to use drugs and alcohol [PDF]
, 2010 Carsey Institute researchers are seeing links between the self-reported substance use and involvement in out-of-school activities. As part of a ten-year tracking survey of high school students in Coos County, New Hampshire, this brief finds that those ...
Sharp, Erin H.
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Re-examining the Impact of Dropping Out on Criminal and Labor Outcomes in Early Adulthood [PDF]
This paper shows that while high school dropouts fare far worse on average than otherwise similar high school completers in early adulthood outcomes such as success in the labor market and future criminal activity, there are important differences within ...
Bjerk, David
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A FOLLOW-UP STUDY OF FIFTY-TWO RICHMOND PUBLIC SCHOOL PUPILS GIVEN PSYCHIATRIC STAFFING DURING THE 1966-1967 SCHOOL YEAR [PDF]
, 1968 This research study is a descriptive study of the effectiveness of the psychiatric staffing as determined by a follow-up study of fifty-two Richmond Public School Pupils given such staffing during the l966-67 school year.
Hopkins, David F. +2 more
core +1 more source