Results 91 to 100 of about 1,521,423 (384)

Targeted Expansion of Treg Cells to Induce Immune Tolerance after Kidney Transplantation

open access: yesAdvanced Science, EarlyView.
A dual‐targeting nanoparticle platform that selectively engages graft stromal cells via CD248 receptors while employing kidney‐ specific promoters (NPHS2) to drive localized IL‐ 2/TGF‐βexpression is developed. This approach achieves three therapeutic objectives:1) intragraft Treg polarization without systemic cytokine exposure;2) reduced dependence on ...
Tong Lu   +18 more
wiley   +1 more source

AN OUTBREAK OF BOTULISM [PDF]

open access: yesJournal of the American Medical Association, 1920
The outbreak of botulism reported here occurred in January, 1920, in an Italian family, living in the Bronx, New York City. The source of the toxin was shown to be a glass jar of factory packed California ripe olives. These olives, consumed as such and also as part of a salad, caused the death of six of the seven members of the family who ate of them ...
openaire   +2 more sources

Working Paper: Are Voters Polarized Along Party Lines About How to Run Elections During the COVID-19 Crisis? [PDF]

open access: yes, 2021
Are voters as polarized as political leaders when it comes to their preferences about how to cast their ballots in November 2020 and their policy positions on how elections should be run in light of the COVID-19 outbreak? Prior research has shown little
HILL, Seth   +4 more
core  

The COVID-19 Outbreak and Affected Countries Stock Markets Response

open access: yesInternational Journal of Environmental Research and Public Health, 2020
This paper evaluates the short-term impact of the coronavirus outbreak on 21 leading stock market indices in major affected countries including Japan, Korea, Singapore, the USA, Germany, Italy, and the UK etc.
Haiyue Liu   +4 more
semanticscholar   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

open access: yesAdvanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei   +12 more
wiley   +1 more source

A case of human survival of rabies, South Africa

open access: yesSouthern African Journal of Infectious Diseases, 2016
Human survival from rabies is exceptionally rare. We report a case of human survival (with severe neurological sequelae) in a child from South Africa.
Jacqueline Weyer   +8 more
doaj   +1 more source

Outbreak Investigations

open access: yes, 2009
The aim of outbreak epidemiology is to study an epidemic in order to gain control over it and to prevent further spread of the disease. Generally outbreak means a “sudden occurrence,” while in the epidemiological sense an outbreak is defined as a sudden increase in the disease frequency, related to time, place, and observed population.
Reintjes, Ralf   +4 more
openaire   +1 more source

Survey of Insomnia and Related Social Psychological Factors Among Medical Staff Involved in the 2019 Novel Coronavirus Disease Outbreak

open access: yesFrontiers in Psychiatry, 2020
Objective The outbreak of the 2019 novel coronavirus disease (COVID-19) not only caused particularly large public health problems, but also caused great psychological distress, especially for medical staff.
Chenxi Zhang   +12 more
semanticscholar   +1 more source

GDF15 Ameliorates Deoxynivalenol‐Induced Anemia by Resolving Ribosomal Stress–Mediated Erythropoietic Arrest

open access: yesAdvanced Science, EarlyView.
Deoxynivalenol induces anemia by disrupting hematopoietic homeostasis and impairing erythroid lineage commitment and differentiation via ribosomal stress–mediated G1/S cell cycle arrest. GDF15 supplementation alleviates this arrest through the β‐catenin–Myc–p21 signaling axis, highlighting GDF15 as a potential therapeutic target for DON‐induced ...
Yan Li   +12 more
wiley   +1 more source

The outbreak of SARS at Tan Tock Seng Hospital--relating epidemiology to control. [PDF]

open access: yes, 2006
INTRODUCTION: The outbreak of severe acute respiratory syndrome (SARS) began after the index case was admitted on 1 March 2003. We profile the cases suspected to have acquired the infection in Tan Tock Seng Hospital (TTSH), focussing on major ...
Ang, Brenda SP   +4 more
core  

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