Results 61 to 70 of about 383,468 (319)
A competitive‐binding paradigm for detection of viruses with the detection of the receptor binding domain of the spike protein as an illustrative example is introduced. Importantly, this approach does not rely on antibodies and therefore is of significance for detecting novel and emerging pathogens. Abstract A liquid crystal (LC)‐based sensing platform
Homa Ghaiedi+4 more
wiley +1 more source
Conflict and Emerging Infectious Diseases
Detection and control of emerging infectious diseases in conflict situations are major challenges due to multiple risk factors known to enhance emergence and transmission of infectious diseases. These include inadequate surveillance and response systems,
Michelle Gayer+3 more
doaj +1 more source
Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin+8 more
wiley +1 more source
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak+2 more
wiley +1 more source
This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf+7 more
wiley +1 more source
Colliding Epidemics and the Rise of Cryptococcosis
Discovered more than 100 years ago as a human pathogen, the Cryptococcus neoformans–Cryptococcus gattii (C. neoformans–C. gattii) complex has seen a large global resurgence in its association with clinical disease in the last 30 years.
Christina C. Chang, Sharon C.-A. Chen
doaj +1 more source
Covid 19 Salgınında Nomofobi ve Psikolojik Sağlamlığın Bazı Değişkenlere Göre İncelenmesi
Amaç: Araştırma Sars-Coronavirus-2 salgınında bireylerde nomofobi ve psikolojik sağlamlığın bazı değişkenlere göre incelenebilmesi amacıyla yapılmıştır.
Burcu Demir Gökmen+2 more
doaj +1 more source
Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication
Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He+6 more
wiley +1 more source
Investigating the Relationship Between World Development Indicators and the Occurrence of Disease Outbreaks in the 21st Century: A Case Study [PDF]
The timely identification of socio-economic sectors vulnerable to a disease outbreak presents an important challenge to the civic authorities and healthcare workers interested in outbreak mitigation measures. This problem was traditionally solved by studying the aberrances in small-scale healthcare data. In this paper, we leverage data driven models to
arxiv