Results 121 to 130 of about 14,971,001 (334)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Vocal Audiometry in Hearing Aid Outcome Measurements [PDF]
, 2009 Single word repetition in quiet differs drastically from everyday conversation, raising validity issues when quality-of-life-type predictions are made starting from classic vocal audiometry.
Corthals, Paul +2 more
core
Impact of Bilingualism on Cognitive Outcome After Stroke [PDF]
, 2015 Suvarna Alladi +9 more
openalex +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Brazilian Journal of AnesthesiologyBackground: Extreme hemodynamic changes, especially intraoperative hypotension (IOH), are common and often prolonged during Liver Transplant (LT) surgery and during initial hours of recovery.
Jacek B. Cywinski +5 more
doaj +1 more source
An Examination of the Application of the Kidney Donor Risk Index in British Columbia
Canadian Journal of Kidney Health and Disease, 2018 Background: The Kidney Donor Risk Index (KDRI) is a continuous measure of deceased donor kidney transplant failure risk that was derived in US patients based on 10 donor characteristics.
Caren Rose +5 more
doaj +1 more source
Control Function Assisted IPW Estimation with a Secondary Outcome in Case-Control Studies [PDF]
, 2014 Case-control studies are designed towards studying associations between risk factors and a single, primary outcome. Information about additional, secondary outcomes is also collected, but association studies targeting such secondary outcomes should ...
Cornelis, Marilyn C. +3 more
core +2 more sources
Significant improvement in the outcome of HCV-infected transplant recipients by avoiding rapid steroid tapering and potent induction immunosuppression [PDF]
, 2006 Marina Berenguer +6 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source