Results 201 to 210 of about 8,937,082 (369)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Genomics of stroke recovery and outcome. [PDF]

J Cereb Blood Flow Metab
Lindgren AG.
europepmc   +1 more source

Effects of Exposure to 21 and 34°C on the Outcome of Overlapping Reproductive Cycles in the Mouse [PDF]

, 1969
Pamela R Pennycuik
openalex   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

Molecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian, Edouard Jarry, Arynne Santos, Quentin Vesval, Lucie Hamel, Rafael Sanchez‐Salas, Alexis Rompré‐Brodeur, Wassim Kassouf, Raghu Rajan, Fadi Brimo, Marie Duclos, Armen Aprikian, Simone Chevalier   +12 more
wiley   +1 more source

LONG-TERM OUTCOMES OF MODERATE TO SEVERE DIFFUSE AXONAL TRAUMATIC BRAIN INJURY: A PROSPECTIVE STUDY. [PDF]

J Rehabil Med Clin Commun
Lannsjö M, Borg J, Lewén A, VON Seth C, Enblad P, Abu Hamdeh S.   +5 more
europepmc   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

International consensus-based core outcome set for airway management clinical trials and observational studies: the Airway Terminology and Outcome Measures (ATOM) protocol. [PDF]

BMJ Open
Hansel J, Fuchs A, Radcliffe G, Sotiriou A, Rivett K, Bohnenblust V, Grimes R, Fally M, Greif R, Cook TM, El Boghdadly K, Airway Terminology and Outcome Measures (ATOM) Group.   +11 more
europepmc   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Validating obstetric triage systems, what are we really measuring - A modified Delphi process introducing outcome measures for obstetric emergency triage systems. [PDF]

BMC Pregnancy Childbirth
Lindroos L, Ernstad E, Sengpiel V.
europepmc   +1 more source

The need for outcomes to be clear - but outcomes of what? [PDF]

Journal of Intellectual Disabilities, 2011
openaire   +3 more sources