Dynamic functional assessment of T cells reveals an early suppression correlating with adverse outcome in polytraumatized patients. [PDF]
Jooss T+14 more
europepmc +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren+4 more
wiley +1 more source
The time course of alpha 2-plasmin inhibitor and plasmin-alpha 2-plasmin inhibitor complex levels in patients with traumatic brain injury. [PDF]
Kanaya T+9 more
europepmc +1 more source
Relation between smallpox vaccination and outcome of pregnancy.
Lauri Saxén, K Cantell, M Hakama
openalex +2 more sources
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh+6 more
wiley +1 more source
Caregiver factors influencing family-based treatment for child and adolescent eating disorders: a systematic review and conceptual model. [PDF]
McCord A, Rice K, Rock A.
europepmc +1 more source
SHORT TERM OUTCOME OF LAPAROSCOPIC VENTRAL RECTOPEXY FOR RECTAL PROLAPSE
Muhammad Naeem
openalex +1 more source
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan+6 more
wiley +1 more source
Association between initial serum cystatin C level and prognosis of aneurysmal subarachnoid hemorrhage. [PDF]
Wang R, Zhang J, Xu J, He M.
europepmc +1 more source