Results 291 to 300 of about 9,686,810 (338)

Treatment patterns, outcomes and its associated factors among seasonal hyper-acute panuveitis cases in one of the largest outbreaks: a hospital-based retrospective study from Nepal. [PDF]

BMC Ophthalmol
Manandhar A, Shrestha S, Poudel M, Banjara P, Oli RU.   +4 more
europepmc   +1 more source

Clinical and Infective Outcome of Parasitologicaly Confirmed Kala-Azar Patients Treated with Sodium Antimony Gluconate

, 1970
Quazi Tarikul Islam, Ahasan Habib, Azizul Haque Azad, HAM Nazmul Ahasan, Md Mahmudur Rahman Siddiqui, Ahmed Hossain   +5 more
openalex   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Analysis of factors influencing short-term outcomes after early interventional therapy for acute ischaemic stroke. [PDF]

BMC Neurol
Wang K, Liu H.
europepmc   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A systematic review of outcomes measured in interventional trials in people with diabetic sensorimotor polyneuropathy. [PDF]

Diabet Med
Chiam G, Smith S, Tu T, Din A, Normahani P, Davies A.   +5 more
europepmc   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Textbook outcome of gastric cancer surgery and lymph node evaluation as its parameter to improve long-term survival. [PDF]

Sci Rep
Cho YS, Kim S, Kim J, Kwak Y, Suh YS, Kong SH, Lee HS, Park DJ, Lee HJ, Kim WH, Yang HK.   +10 more
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Iloprost therapy achieves good clinical and radiological short and mid-term outcomes in patients with idiopathic aseptic osteonecrosis of the knee joint also in ARCO level II. [PDF]

Arch Orthop Trauma Surg
Kirschbaum S, Perka C, El-Kayali M, Gwinner C, Walter-Rittel TC, Soujon M, Donner S.   +6 more
europepmc   +1 more source