Results 31 to 40 of about 448,885 (232)

Do it fast! Early access to specialized care improved long-term outcomes in rheumatoid arthritis: data from the REAL multicenter observational study

Advances in Rheumatology, 2023
Background Early rheumatoid arthritis (RA) offers an opportunity for better treatment outcomes. In real-life settings, grasping this opportunity might depend on access to specialized care.
Cleandro Pires Albuquerque, Ana Paula Monteiro Gomides Reis, Ana Beatriz Vargas Santos, Manoel Barros Bértolo, Paulo Louzada Júnior, Rina Dalva Neubarth Giorgi, Sebastião Cezar Radominski, Maria Fernanda B. Resende Guimarães, Karina Rossi Bonfiglioli, Maria de Fátima L Cunha Sauma, Ivânio Alves Pereira, Claiton Viegas Brenol, Licia Maria Henrique Mota, Leopoldo Santos-Neto, Geraldo Rocha Castelar Pinheiro   +14 more
doaj   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Big Data-Planetary Health approach for evaluating the Brazilian Dengue Control Program

Revista de Saúde Pública
OBJECTIVE This study aims to integrate the concepts of planetary health and big data into the Donabedian model to evaluate the Brazilian dengue control program in the state of São Paulo.
Fernando Xavier, Gerson Laurindo Barbosa, Cristiano Corrêa de Azevedo Marques, Antonio Mauro Saraiva   +3 more
doaj   +2 more sources

Establishing Inter-Rater Reliability of the Occupation-Centered Intervention Assessment for Student Observation of Rehabilitation Interventions

Journal of Occupational Therapy Education, 2021
The Occupation-Centered Intervention Assessment (OCIA) is a tool designed to capture and rank occupational therapy interventions through an occupational lens to improve occupational therapy students’ professional reasoning skills.
Vanessa D. Jewell, Joy Burkley, Taylor Wienkes, Ted K. Kaufman   +3 more
doaj   +1 more source

Development of a Quality Management Model and Self-assessment Questionnaire for Hybrid Health Care: Concept Mapping Study

JMIR Formative Research, 2022
BackgroundWorking with eHealth requires health care organizations to make structural changes in the way they work. Organizational structure and process must be adjusted to provide high-quality care. This study is a follow-up study
Rosian Tossaint-Schoenmakers, Marise J Kasteleyn, Anneloek Rauwerdink, Niels Chavannes, Sofie Willems, Esther P W A Talboom-Kamp   +5 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Preventive and therapeutic assessment program for mucositis in patients with cancer: promising advances in stomatological care

Brazilian Journal of Oncology
OBJECTIVES: We propose a preventive and therapeutic assessment program for mucositis in patients with cancer based on a comprehensive review of scientific evidence. MATERIAL AND METHODS: This methodological study, designed as a non-systematic
Renata Lemos Ferrari, Rafaela Mota Peixoto, Tauana Batista Fernandes, Luana Farnese Machado Abreu, Ana Carolina de Araujo Tolentino Felizardo, Lourenço Duarte Siqueira, Ana Maria Dias da Costa, Bianca Silva de Andrade, Clara de Figueiredo Lopes, Daniele Ferreira Araujo, Leticia Fulgencio de Araújo, Ruan Soares da Silva, Flavia Santos Dumont Sorice, Sarah Ananda Gomes, Bruno Lemos Ferrari, Carlos Gil Moreira Ferreira, Mariana Tosello Laloni, Pedro Rafael Martins De-Marchi, Cristiane Decat Bergerot   +18 more
doaj   +1 more source

Breast cancer screening program for risk groups: facts and perspectives

Revista Brasileira de Enfermagem, 2021
Objectives: to measure the frequency and compliance of breast cancer screening, according to the risk for this disease. Methods: a cross-sectional study with 950 female users of 38 public Primary Health Care services in São Paulo, between October and ...
Carla Andréia Vilanova Marques, Elisabeth Níglio de Figueiredo, Maria Gaby Rivero de Gutiérrez   +2 more
doaj   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Patient Assessment Chronic Illness Care (PACIC) and its associations with quality of life among Swiss patients with systemic sclerosis: a mixed methods study

Orphanet Journal of Rare Diseases, 2023
Background The Chronic Care Model (CCM) is a longstanding and widely adopted model guiding chronic illness management. Little is known about how CCM elements are implemented in rare disease care or how patients’ care experiences relate to health-related ...
Agnes Kocher, Michael Simon, Andrew A. Dwyer, Catherine Blatter, Jasmina Bogdanovic, Patrizia Künzler-Heule, Peter M. Villiger, Diana Dan, Oliver Distler, Ulrich A. Walker, Dunja Nicca   +10 more
doaj   +1 more source