Results 41 to 50 of about 797,426 (292)

Preventive and therapeutic assessment program for mucositis in patients with cancer: promising advances in stomatological care

Brazilian Journal of Oncology
OBJECTIVES: We propose a preventive and therapeutic assessment program for mucositis in patients with cancer based on a comprehensive review of scientific evidence. MATERIAL AND METHODS: This methodological study, designed as a non-systematic
Renata Lemos Ferrari, Rafaela Mota Peixoto, Tauana Batista Fernandes, Luana Farnese Machado Abreu, Ana Carolina de Araujo Tolentino Felizardo, Lourenço Duarte Siqueira, Ana Maria Dias da Costa, Bianca Silva de Andrade, Clara de Figueiredo Lopes, Daniele Ferreira Araujo, Leticia Fulgencio de Araújo, Ruan Soares da Silva, Flavia Santos Dumont Sorice, Sarah Ananda Gomes, Bruno Lemos Ferrari, Carlos Gil Moreira Ferreira, Mariana Tosello Laloni, Pedro Rafael Martins De-Marchi, Cristiane Decat Bergerot   +18 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

Assessing Process and Outcomes: Evaluating Community-Based Participatory Research

Progress in Community Health Partnerships: Research, Education, and Action, 2008
Background: The California Breast Cancer Research Program (CBCRP) Community Research Collaboration (CRC) Awards fund research projects conducted by partnerships between community members and academically trained research scientists. Objectives: We sought to determine the relationship, if any, between the collaborative process of conducting the CRC ...
Plumb, Marj, Collins, Natalie, Cordeiro, Janna N, Kavanaugh-Lynch, Mhel   +3 more
openaire   +4 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Evolution of Process and Outcome Measures during an Enhanced Recovery after Thoracic Surgery Program

Journal of Chest Surgery, 2022
Background: A time course analysis was undertaken to evaluate how perioperative process- of-care and outcome measures evolved after implementation of an enhanced recovery after thoracic surgery (ERATS) program.
Alex Lee, Nazgol Seyednejad, Yaseen Al Lawati, Amanda Mattice, Caitlin Anstee, Mark Legacy, Sebastien Gilbert, Donna E. Maziak, Ramanadhan S. Sundaresan, Patrick J. Villeneuve, Calvin Thompson, Andrew J. E. Seely   +11 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source